DET1

Gene Symbol	DET1
Entrez Gene	55070
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	de-etiolated homolog 1 (Arabidopsis)
Other Description	DET1 homolog|de-etiolated 1|de-etiolated-1 homolog
Swissprots	Q9NWD5 B3KNN6 Q2VPC0 Q7L5Y6
Accessions	CAD34982 CAE88994 EAX02003 EAX02004 EAX02005 EAX02006 Q7L5Y6 AB073887 AK000965 BAA91447 AK054603 BAG51398 BC001242 AAH01242 BC064591 BC073867 BC109060 AAI09061 BC109061 AAI09062 DA655836 XM_011521747 XP_011520049 XM_011521748 XP_011520050 XM_011521749 XP_011520051 XM_011521750 XP_011520052 XM_011521751 XP_011520053 NM_001144074 NP_001137546 NM_017996 NP_060466 NR_026645
Function	Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation. {ECO:0000269|PubMed:14739464}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Highly expressed in the ovary, some lymphoid organs and resting leukocytes. {ECO:0000269|PubMed:14739464}.
Top Pathways	Ubiquitin mediated proteolysis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DET1 CRISPR/Cas9 KO Plasmid (h) - sc-406735 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

DET1 HDR Plasmid (h) - sc-406735-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

DET1 Double Nickase Plasmid (h) - sc-406735-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

DET1 Double Nickase Plasmid (h2) - sc-406735-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

DET1 CRISPR Activation Plasmid (h) - sc-406735-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

DET1 CRISPR Activation Plasmid (h2) - sc-406735-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

DET1 Lentiviral Activation Particles (h) - sc-406735-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

DET1 Lentiviral Activation Particles (h2) - sc-406735-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

DET1 siRNA (h) - sc-89981 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

DET1 shRNA Plasmid (h) - sc-89981-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

DET1 shRNA (h) Lentiviral Particles - sc-89981-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU008511 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1242 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1242 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04297 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04297

DET1 siRNA (Human) - CRJ0445 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

DET1 - MBS8233521 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human DET1 (NM_017996.3) - SHH277253 from Creative biogene Category siRNA Species Reactivities Human

DET1 CRISPR/Cas9 KO Plasmid (h2) - sc-406735-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

DET1 HDR Plasmid (h2) - sc-406735-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Human DET1 siRNA - orb270946 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

DET1 shRNA Plasmid (Human) - CHJ0445 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

DET1 miRNA 3'UTR clone - MiUTR3H-10170 from Creative biogene Species Reactivities Human

DET1 miRNA 3'UTR clone - MiUTR3H-10171 from Creative biogene Species Reactivities Human

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