| Gene Symbol |
Pea15
|
| Entrez Gene |
364052
|
| Alt Symbol |
Pea15a
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
phosphoprotein enriched in astrocytes 15
|
| Other Description |
15 kDa phosphoprotein enriched in astrocytes|astrocytic phosphoprotein PEA-15|phosphoprotein enriched in astrocytes 15A
|
| Swissprots |
Q5U318 Q78ZC9
|
| Accessions |
EDL94690 EDL94691 EDL94692 Q5U318 AJ243949 CAB51573 BC085766 AAH85766 FQ235065 NM_001013231 NP_001013249
|
| Function |
Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm. Note=Associated with microtubules. {ECO:0000250}.
|