Gene Symbol | Pea15 |
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Entrez Gene | 364052 |
Alt Symbol | Pea15a |
Species | Rat |
Gene Type | protein-coding |
Description | phosphoprotein enriched in astrocytes 15 |
Other Description | 15 kDa phosphoprotein enriched in astrocytes|astrocytic phosphoprotein PEA-15|phosphoprotein enriched in astrocytes 15A |
Swissprots | Q5U318 Q78ZC9 |
Accessions | EDL94690 EDL94691 EDL94692 Q5U318 AJ243949 CAB51573 BC085766 AAH85766 FQ235065 NM_001013231 NP_001013249 |
Function | Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Note=Associated with microtubules. {ECO:0000250}. |
Recombinant Rat Astrocytic phosphoprotein PEA-15(Pea15) - CSB-YP736012RA CSB-EP736012RA CSB-BP736012RA CSB-MP736012RA from Cusabio
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Astrocytic phosphoprotein PEA-15 (Pea15) , Recombinant Protein - MBS1317037 from MyBioSource
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Recombinant Rat PEA15A Protein - PEA15A-4367R from Creative Biomart
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