NDE1

Gene Symbol NDE1
Entrez Gene 54820
Alt Symbol HOM-TES-87, LIS4, MHAC, NDE, NUDE, NUDE1
Species Human
Gene Type protein-coding
Description nudE neurodevelopment protein 1
Other Description LIS1-interacting protein NUDE1, rat homolog|nuclear distribution protein nudE homolog 1|nudE nuclear distribution E homolog 1|nudE nuclear distribution gene E homolog 1
Swissprots Q9NXR1 Q49AQ2
Accessions EAW53931 EAW53932 EAW53933 Q9NXR1 AF124431 AK000108 BAA90949 AK025815 AK127927 BC001421 AAH01421 BC033900 AAH33900 BP271845 KJ534887 AHW56527 KJ534967 AHW56607 KJ534991 AHW56631 KJ535028 AHW56667 XM_005255396 XP_005255453 XM_006720897 XP_006720960 XM_006720898 XP_006720961 XM_006720899 XP_006720962 XM_006720900 XP_006720963 XM_006725200 XP_006725263 XM_006725201 XP_006725264 XM_006725202 XP_006725265 XM_006725203 XP_006725266 XM_006725204 XP_006725267 XM_011522549 XP_011520851 XM_011522550 XP_011520852 XM_011522551 XP_011520853 XM_011522552 XP_011520854 XM_011522553 XP_011520855 XM_011522554 XP_011520856 XM_011546707 XP_011545009 XM_011546708 XP_011545010 XM_011546709 XP_011545011 XM_011546710 XP_011545012 XM_011546711 XP_011545013 XM_011546712 XP_011545014 NM_001143979 NP_001137451 NM_017668 NP_060138
Function Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post- mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex. {ECO:0000269|PubMed:17600710, ECO:0000269|PubMed:21529752}.
Subcellular Location Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Note=Localizes to the interphase and S phase centrosome. During mitosis, partially associated with the mitotic spindle. Concentrates at the plus ends of microtubules coincident with kinetochores in metaphase and anaphase in a CENPF- dependent manner. Also localizes to the cleavage furrow during cytokinesis. manner. Also localizes to the cleavage furrow during cytokinesis.
Tissue Specificity Expressed in the neuroepithelium throughout the developing brain, including the cerebral cortex and cerebellum. {ECO:0000269|PubMed:21529752}.

NUDE1 CRISPR/Cas9 KO Plasmid (h) - sc-409971 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDE1 HDR Plasmid (h) - sc-409971-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDE1 Double Nickase Plasmid (h) - sc-409971-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDE1 Double Nickase Plasmid (h2) - sc-409971-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDE1 CRISPR Activation Plasmid (h) - sc-409971-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDE1 CRISPR Activation Plasmid (h2) - sc-409971-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDE1 Lentiviral Activation Particles (h) - sc-409971-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDE1 Lentiviral Activation Particles (h2) - sc-409971-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDE1 siRNA (h) - sc-106779 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NUDE1 shRNA Plasmid (h) - sc-106779-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NUDE1 shRNA (h) Lentiviral Particles - sc-106779-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU034101 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15118 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15118 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07414 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07414

NDE1 siRNA (Human) - CRJ0240 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NDE1 RNAi - H00054820-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human NDE1 (NM_017668.2) - SHH350264 from Creative biogene

Category siRNA
Species Reactivities Human

NDE1 shRNA Plasmid (Human) - CHJ0240 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NDE1 miRNA 3'UTR clone - MiUTR4H-TG05899 from Creative biogene

Species Reactivities Human
Search more