KDM4B

Gene Symbol KDM4B
Entrez Gene 23030
Alt Symbol JMJD2B, TDRD14B
Species Human
Gene Type protein-coding
Description lysine (K)-specific demethylase 4B
Other Description jmjC domain-containing histone demethylation protein 3B|jumonji domain containing 2B|jumonji domain-containing protein 2B|lysine-specific demethylase 4B|tudor domain containing 14B
Swissprots D6W631 Q9UF40 Q6P3R5 O75274 Q9P1V1 O94953 B9EGN8
Accessions AAF31271 EAW69180 EAW69181 EAW69182 EAW69183 O94953 AB020683 BAA74899 AF052144 AK026040 AK126854 BAG54381 AL133622 CAB63748 BC015378 BC040014 BC046167 BC063889 AAH63889 BC136611 AAI36612 BC144292 AAI44293 BF917212 DA379611 DB636535 XM_005259521 XP_005259578 XM_005259522 XP_005259579 XM_011527814 XP_011526116 XM_011527815 XP_011526117 XM_011527816 XP_011526118 XM_011527817 XP_011526119 XM_011527818 XP_011526120 XM_011527819 XP_011526121 XM_011527820 XP_011526122 XM_011527821 XP_011526123 XM_011527822 XP_011526124 XR_936167 NM_015015 NP_055830
Function Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. {ECO:0000269|PubMed:16603238}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00537, ECO:0000269|PubMed:15927959}.

SignalSilence ® JMJD2B siRNA II - 7062 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from 293T cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® JMJD2B siRNA I #7435 (+), or SignalSilence ® JMJD2B siRNA II (+), using JMJD2B (D7E6) Rabbit mAb #8639 (upper) or GAPDH (D16H11) XP ® Rabbit mAb #5174 (lower). The JMJD2B (D7E6) Rabbit mAb confirms silencing of JMJD2B expression, while the GAPDH (D16H11) XP ® Rabbit mAb is used as a loading control.

SignalSilence ® JMJD2B siRNA I - 7435 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from 293T cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® JMJD2B siRNA I (+), or SignalSilence ® JMJD2B siRNA II #7062 (+), using JMJD2B (D7E6) Rabbit mAb #8639 (upper) or GAPDH (D16H11) XP ® Rabbit mAb #5174 (lower). The JMJD2B (D7E6) Rabbit mAb confirms silencing of JMJD2B expression, while the GAPDH (D16H11) XP ® Rabbit mAb is used as a loading control.

JMJD2B CRISPR/Cas9 KO Plasmid (h) - sc-405385 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2B HDR Plasmid (h) - sc-405385-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2B Double Nickase Plasmid (h) - sc-405385-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2B Double Nickase Plasmid (h2) - sc-405385-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2B CRISPR Activation Plasmid (h) - sc-405385-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2B CRISPR Activation Plasmid (h2) - sc-405385-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2B Lentiviral Activation Particles (h) - sc-405385-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2B Lentiviral Activation Particles (h2) - sc-405385-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2B siRNA (h) - sc-62517 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JMJD2B shRNA Plasmid (h) - sc-62517-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JMJD2B shRNA (h) Lentiviral Particles - sc-62517-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JMJD2B RNAi - H00023030-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU136991 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11031 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11031 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

KDM4B siRNA (Human) - CRH7943 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KDM4B (NM_015015.2) - SHH324203 from Creative biogene

Category siRNA
Species Reactivities Human

KDM4B shRNA Plasmid (Human) - CHH7943 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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