Gene Symbol | KDM4B |
---|---|
Entrez Gene | 23030 |
Alt Symbol | JMJD2B, TDRD14B |
Species | Human |
Gene Type | protein-coding |
Description | lysine (K)-specific demethylase 4B |
Other Description | jmjC domain-containing histone demethylation protein 3B|jumonji domain containing 2B|jumonji domain-containing protein 2B|lysine-specific demethylase 4B|tudor domain containing 14B |
Swissprots | D6W631 Q9UF40 Q6P3R5 O75274 Q9P1V1 O94953 B9EGN8 |
Accessions | AAF31271 EAW69180 EAW69181 EAW69182 EAW69183 O94953 AB020683 BAA74899 AF052144 AK026040 AK126854 BAG54381 AL133622 CAB63748 BC015378 BC040014 BC046167 BC063889 AAH63889 BC136611 AAI36612 BC144292 AAI44293 BF917212 DA379611 DB636535 XM_005259521 XP_005259578 XM_005259522 XP_005259579 XM_011527814 XP_011526116 XM_011527815 XP_011526117 XM_011527816 XP_011526118 XM_011527817 XP_011526119 XM_011527818 XP_011526120 XM_011527819 XP_011526121 XM_011527820 XP_011526122 XM_011527821 XP_011526123 XM_011527822 XP_011526124 XR_936167 NM_015015 NP_055830 |
Function | Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. {ECO:0000269|PubMed:16603238}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00537, ECO:0000269|PubMed:15927959}. |
JMJD2B Antibody - 2898 from Cell Signaling Technology
|
||||||||||
JMJD2B (D7E6) Rabbit mAb - 8639 from Cell Signaling Technology
|
||||||||||
JMJD2B (G-20) - sc-54549 from Santa Cruz Biotechnology
|
||||||||||
JMJD2B (H-200) - sc-67192 from Santa Cruz Biotechnology
|
||||||||||
JMJD2B (Q-17) - sc-54477 from Santa Cruz Biotechnology
|
||||||||||
Anti-KDM4B / JMJD2B (phospho T305) antibody - ab103410 from Abcam
|
||||||||||
Anti-KDM4B / JMJD2B antibody - ab27531 from Abcam
|
||||||||||
Anti-KDM4B / JMJD2B antibody - ab91549 from Abcam
|
||||||||||
Anti-KDM4B / JMJD2B antibody - ab103129 from Abcam
|
||||||||||
Anti-KDM4B / JMJD2B antibody - ab80473 from Abcam
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (phospho-Ser566) - LS-C163627 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (phospho-Ser622) - LS-C163628 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa281-306, AP) - LS-C260647 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa281-306, Biotin) - LS-C260648 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa281-306, FITC) - LS-C260650 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa281-306, APC) - LS-C260649 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa359-408) - LS-C112169 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa684-733) - LS-C112189 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa281-306, Azide-free, HRP) - LS-C260651 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa281-306, PE) - LS-C260652 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa428-459) - LS-C165361 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa428-459, APC) - LS-C260660 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa428-459, FITC) - LS-C260662 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa428-459, Azide-free, HRP) - LS-C260663 from LifeSpan Bioscience
|
||||||||||
Anti-KDM4B / JMJD2B Antibody (aa428-459, AP) - LS-C260659 from LifeSpan Bioscience
|