Gene Symbol | KDM4B |
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Entrez Gene | 23030 |
Alt Symbol | JMJD2B, TDRD14B |
Species | Human |
Gene Type | protein-coding |
Description | lysine (K)-specific demethylase 4B |
Other Description | jmjC domain-containing histone demethylation protein 3B|jumonji domain containing 2B|jumonji domain-containing protein 2B|lysine-specific demethylase 4B|tudor domain containing 14B |
Swissprots | D6W631 Q9UF40 Q6P3R5 O75274 Q9P1V1 O94953 B9EGN8 |
Accessions | AAF31271 EAW69180 EAW69181 EAW69182 EAW69183 O94953 AB020683 BAA74899 AF052144 AK026040 AK126854 BAG54381 AL133622 CAB63748 BC015378 BC040014 BC046167 BC063889 AAH63889 BC136611 AAI36612 BC144292 AAI44293 BF917212 DA379611 DB636535 XM_005259521 XP_005259578 XM_005259522 XP_005259579 XM_011527814 XP_011526116 XM_011527815 XP_011526117 XM_011527816 XP_011526118 XM_011527817 XP_011526119 XM_011527818 XP_011526120 XM_011527819 XP_011526121 XM_011527820 XP_011526122 XM_011527821 XP_011526123 XM_011527822 XP_011526124 XR_936167 NM_015015 NP_055830 |
Function | Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. {ECO:0000269|PubMed:16603238}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00537, ECO:0000269|PubMed:15927959}. |
Active human KDM4B / JMJD2B protein fragment - ab198149 from Abcam
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Human KDM4B / JMJD2B peptide - ab30598 from Abcam
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Mouse KDM4B / JMJD2B protein fragment - ab139634 from Abcam
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KDM4B / JMJD2B Antibody Blocking Peptide - LS-E1321 from LifeSpan Bioscience
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KDM4B / JMJD2B Antibody Blocking Peptide - LS-E30767 from LifeSpan Bioscience
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KDM4B / JMJD2B Antibody Blocking Peptide - LS-E7468 from LifeSpan Bioscience
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KDM4B / JMJD2B Antibody Blocking Peptide - LS-E21298 from LifeSpan Bioscience
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KDM4B / JMJD2B Antibody Blocking Peptide - LS-E21355 from LifeSpan Bioscience
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KDM4B / JMJD2B Antibody Blocking Peptide - LS-E10229 from LifeSpan Bioscience
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KDM4B / JMJD2B Blocking Peptide - LS-E10416 from LifeSpan Bioscience
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KDM4B / JMJD2B Antibody Blocking Peptide - LS-E10104 from LifeSpan Bioscience
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JMJD2B Blocking Peptide - NBP1-76314PEP from Novus Biologicals
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JMJD2B-Antibody-N-term-Blocking-peptide - BP11950a from Abgent, a WuXi AppTec company
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Phospho-JMJD2BS622-Antibody-Blocking-peptide - BP3723a from Abgent, a WuXi AppTec company
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JMJD2B-Antibody-N-term-Blocking-Peptide - BP9393a from Abgent, a WuXi AppTec company
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JMJD2B-Antibody-T305-Blocking-Peptide - BP9624a from Abgent, a WuXi AppTec company
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Phospho-JMJD2B-T305-Antibody-Blocking-peptide - BP9960a from Abgent, a WuXi AppTec company
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JMJD2B Blocking Peptide - 33R-2124 from Fitzgerald
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JMJD2B Blocking Peptide - 33R-8316 from Fitzgerald
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JMJD2B / KDM4B Control Peptide - AP30461CP-N from Acris Antibodies
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JMJD2B Peptide - 5375P from ProSci
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Recombinant Human KDM4B - KDM4B-953H from Creative Biomart
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KDM4B protein-GST fusion - 010-001-S34 from Rockland Immunochemicals Inc
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KDM4B protein-GST fusion - 010-001-S34S from Rockland Immunochemicals Inc
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Recombinant Human Lysine-specific demethylase 4B(KDM4B) ,partial - CSB-YP012138HU CSB-EP012138HU CSB-BP012138HU CSB-MP012138HU from Cusabio
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