| Gene Symbol |
RNASEH2A
|
| Entrez Gene |
10535
|
| Alt Symbol |
AGS4, JUNB, RNASEHI, RNHIA, RNHL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ribonuclease H2, subunit A
|
| Other Description |
RNase H(35)|RNase H2 subunit A|RNase HI large subunit|aicardi-Goutieres syndrome 4 protein|ribonuclease H2 subunit A|ribonuclease H2, large subunit|ribonuclease HI large subunit|ribonuclease HI subunit A|ribonuclease HI, large subunit
|
| Swissprots |
O75792 B2RCY1 Q96F11
|
| Accessions |
EAW84313 O75792 AK315327 BAG37728 AY363912 AAQ64005 BC011748 AAH11748 BE560339 BG825340 BM664190 CB240995 CR456841 CAG33122 Z97029 CAB09725 XM_006722619 XP_006722682 NM_006397 NP_006388
|
| Function |
Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. {ECO:0000269|PubMed:16845400, ECO:0000269|PubMed:21177858}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Top Pathways |
DNA replication
|