Gene Symbol | ERLIN1 |
---|---|
Entrez Gene | 10613 |
Alt Symbol | C10orf69, Erlin-1, KE04, KEO4, SPFH1, SPG62 |
Species | Human |
Gene Type | protein-coding |
Description | ER lipid raft associated 1 |
Other Description | Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9|SPFH domain family, member 1|SPFH domain-containing protein 1|endoplasmic reticulum lipid raft-associated protein 1|erlin-1|stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1 |
Swissprots | O75477 Q53HV0 B0QZ42 |
Accessions | EAW49846 EAW49847 O75477 AF064093 AAC26658 AK056574 AK127017 AK222480 BAD96200 AK298427 BAG60649 AK315580 BAG37953 BC031791 AAH31791 BP280488 BQ101058 BU192550 DQ894532 ABM85458 EU176273 ABW03724 XM_005269442 XP_005269499 XM_011539170 XP_011537472 XM_011539171 XP_011537473 NM_001100626 NP_001094096 NM_006459 NP_006450 |
Function | Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). {ECO:0000269|PubMed:19240031}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:11118313, ECO:0000269|PubMed:16835267, ECO:0000269|PubMed:19240031}; Single-pass type II membrane protein {ECO:0000269|PubMed:11118313, ECO:0000269|PubMed:16835267, ECO:0000269|PubMed:19240031}. Note=Associated with lipid raft-like domains of the endoplasmic reticulum membrane. |
Tissue Specificity | Expressed in heart, placenta, liver, kidney, pancreas, prostate, testis, ovary and small intestine. {ECO:0000269|PubMed:11118313}. |
Erlin-1 Antibody - 2958 from Cell Signaling Technology
|
||||||||
SPFH1 (A-17) - sc-244210 from Santa Cruz Biotechnology
|
||||||||
SPFH1 (C-18) - sc-244211 from Santa Cruz Biotechnology
|
||||||||
SPFH1 (D-16) - sc-244209 from Santa Cruz Biotechnology
|
||||||||
Anti-ERLIN1 antibody - ab171372 from Abcam
|
||||||||
Anti-ERLIN1 / SPFH1 Antibody (aa244-273, APC) - LS-C235042 from LifeSpan Bioscience
|
||||||||
Anti-ERLIN1 / SPFH1 Antibody (aa244-273, AP) - LS-C235043 from LifeSpan Bioscience
|
||||||||
Anti-ERLIN1 / SPFH1 Antibody (aa74-123) - LS-C80925 from LifeSpan Bioscience
|
||||||||
Anti-ERLIN1 / SPFH1 Antibody (aa244-273, Biotin) - LS-C235044 from LifeSpan Bioscience
|
||||||||
Anti-ERLIN1 / SPFH1 Antibody (aa244-273, FITC) - LS-C235045 from LifeSpan Bioscience
|
||||||||
Anti-ERLIN1 / SPFH1 Antibody (aa245-275) - LS-C321176 from LifeSpan Bioscience
|
||||||||
Anti-ERLIN1 / SPFH1 Antibody (aa244-273, Azide-free, HRP) - LS-C249930 from LifeSpan Bioscience
|
||||||||
Anti-ERLIN1 / SPFH1 Antibody (aa244-273, PE) - LS-C235046 from LifeSpan Bioscience
|
||||||||
Anti-ERLIN1 / SPFH1 Antibody (aa329-343) - LS-C112846 from LifeSpan Bioscience
|
||||||||
Anti-ERLIN1 / SPFH1 Antibody (aa244-273) - LS-C167810 from LifeSpan Bioscience
|
||||||||
ERLIN1 Antibody - NBP1-88539 from Novus Biologicals
|
||||||||
ERLIN1 Antibody - NBP2-16368 from Novus Biologicals
|
||||||||
ERLIN1 Antibody - NBP1-45206 from Novus Biologicals
|
||||||||
Anti-ERLIN1 antibody produced in rabbit - SAB2100706 from Sigma-Aldrich
|
||||||||
Anti-ERLIN1 (C-terminal) antibody produced in goat - SAB2501274 from Sigma-Aldrich
|
||||||||
Anti-ERLIN1 antibody produced in rabbit - HPA011252 from Sigma-Aldrich
|
||||||||
ERLIN1 antibody - N-terminal region (ARP46725_P050) - ARP46725_P050 from Aviva Systems Biology
|
||||||||
ERLIN1-Antibody-Center - AP13078c from Abgent, a WuXi AppTec company
|
||||||||
KEO4--ERLIN1-Antibody - AF2187a from Abgent, a WuXi AppTec company
|
||||||||
ERLIN1 antibody - GTX120815 from GeneTex
|