Cmklr1

Gene Symbol	Cmklr1
Entrez Gene	14747
Alt Symbol	ChemR23, DEZ, Gpcr27, mcmklr1
Species	Mouse
Gene Type	protein-coding
Description	chemokine-like receptor 1
Other Description	G-protein coupled receptor 27|G-protein coupled receptor DEZ|chemerin receptor|chemokine receptor-like 1
Swissprots	P97468
Accessions	EDL19943 P97468 AK158424 BAE34502 BC100612 AAI00613 BY347978 U79525 AAB53789 XM_006530164 XP_006530227 XM_006530165 XP_006530228 XM_006530166 XP_006530229 NM_008153 NP_032179
Function	Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF- kappa-B (By similarity). Positively regulates adipogenesis and adipocyte metabolism. {ECO:0000250, ECO:0000269|PubMed:15753205, ECO:0000269|PubMed:16863918, ECO:0000269|PubMed:17635925}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:16863918}; Multi-pass membrane protein {ECO:0000269|PubMed:16863918}.
Tissue Specificity	Expressed in the differentiated adipocytes (at protein level). Ubiquitous. Highly expressed in adipose tissue and immature plasmacytoid dendritic cells (DCs) and at lower levels in myeloid DCs, macrophages, and NK cells. Expressed on macrophages isolated from different tissues, including peritoneal cavities, pleural cavities and spleen. {ECO:0000269|PubMed:16863918, ECO:0000269|PubMed:17635925, ECO:0000269|PubMed:17767914, ECO:0000269|PubMed:18242188, ECO:0000269|PubMed:19841182}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

ChemR23 (H-6) - sc-398769 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

ChemR23 (E-19) - sc-32652 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-CMKLR1 antibody - ab203384 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CMKLR1 antibody [1G10] - ab176378 from Abcam Prices $376.00 Sizes 250 µg Host Rat Clonality Monoclonal Clone 1G10

ChemR23/CMKLR1 Antibody (BZ194) - NBP1-43233 from Novus Biologicals Prices $299.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (477806) [Phycoerythrin] - FAB7610P from Novus Biologicals Prices $289.00 Sizes 100 tests Host Rat Clonality Monoclonal Clone 477806

ChemR23/CMKLR1 Antibody (477806) [Alexa Fluor® 488] - FAB7610G from Novus Biologicals Prices $309.00 Sizes 100 tests Host Rat Clonality Monoclonal Clone 477806

ChemR23/CMKLR1 Antibody (BZ194) [Allophycocyanin] - NBP1-43233APC from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [PE] - NBP1-43233PE from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [DyLight 350] - NBP1-43233UV from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [DyLight 680] - NBP1-43233FR from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [7C] - NBP1-43233V2 from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [DyLight 755] - NBP1-43233IR from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [DyLight 405] - NBP1-43233V from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor (R) 700] - NBP1-43233AF700 from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor (R) 647] - NBP1-43233AF647 from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor (R) 488] - NBP1-43233AF488 from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor (R) 405] - NBP1-43233AF405 from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [PerCP] - NBP1-43233PCP from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [DyLight 488] - NBP1-43233G from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

ChemR23/CMKLR1 Antibody (BZ194) [DyLight 405LS] - NBP1-43233V3 from Novus Biologicals Host Rat Clonality Monoclonal Clone BZ194

CMKLR1 Polyclonal Antibody - bs-10185R from Bioss Prices $279.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

CMKLR1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-10185R-A350 from Bioss Prices $379.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

CMKLR1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-10185R-A488 from Bioss Prices $379.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

CMKLR1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-10185R-A555 from Bioss Prices $379.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

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