RQCD1

Gene Symbol	RQCD1
Entrez Gene	9125
Alt Symbol	CNOT9, CT129, RCD-1, RCD1
Species	Human
Gene Type	protein-coding
Description	RCD1 required for cell differentiation1 homolog (S. pombe)
Other Description	CCR4-NOT transcription complex subunit 9|cancer/testis antigen 129|cell differentiation protein RCD1 homolog|protein involved in sexual development
Swissprots	Q92600 Q96IX4 B2RPI0 B5MDQ4 B7Z1E5
Accessions	BAA13508 EAW70624 EAW70625 Q92600 AA806815 AB500892 BAJ07307 AK293281 BAH11481 AK296037 BAG58803 AK316567 BAG38156 BC007102 AAH07102 BC137455 AAI37456 BC137456 AAI37457 DC299874 XM_011512138 XP_011510440 NM_001271634 NP_001258563 NM_001271635 NP_001258564 NM_005444 NP_005435 NR_073390
Function	Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all. {ECO:0000250, ECO:0000269|PubMed:17189474, ECO:0000269|PubMed:18180299}.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm, P-body {ECO:0000250}. Note=NANOS2 promotes its localization to P-body. {ECO:0000250}.
Tissue Specificity	Detected in spleen, thymus, prostate, testis, ovary and intestine. {ECO:0000269|PubMed:9447985}.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RQCD1 full length protein - ab101208 from Abcam Category Protein Source E. coli Species Human

RCD1 / RQCD1 Antibody Blocking Peptide - LS-E5356 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RCD1 / RQCD1 Antibody Blocking Peptide - LS-E24065 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RQCD1 Recombinant Protein - H00009125-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human RQCD1 Protein - NBP1-50873 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

RQCD1-Antibody-Center-Blocking-Peptide - BP17848c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RQCD1 Protein (OPPA02633) - OPPA02633 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human RQCD1 protein - orb169221 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

RQCD1 protein (His tag) - 80R-1548 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

RQCD1 (1-299, His-tag) - AR09727PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

RQCD1 (1-299, His-tag) - AR09727PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

RQCD1 - H00009125-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RQCD1 - H00009125-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RQCD1, 1-299aa, Human, His tag, E.coli - 01-P0787 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

RQCD1 fusion protein - ag18507 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

RQCD1 fusion protein - Ag18197 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

RQCD1 Human - PRPS-015 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human RQCD1 Protein - BP002268-PRO-008 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

RQCD1, 1-299aa, Recombinant Protein - GWB-P1251C from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

RQCD1 Human Protein - GWB-BSP624 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human RQCD1, His-tagged - RQCD1-2883H from Creative Biomart Category Protein Source E.coli.

RQCD1 - NKX-RP4 from Reagent Proteins Category Protein Prices $364.00, $2,898.00 Sizes 20.00 µg, 1 mg Source E.coli

RQCD1 1-299aa - CMB-620 from Reagent Proteins Category Protein Prices $469.00, $889.00 Sizes 100.00 µg, 500 µg Source E.coli Species Human

Recombinant Human Cell differentiation protein RCD1 homolog(RQCD1) - CSB-YP842140HU CSB-EP842140HU CSB-BP842140HU CSB-MP842140HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Pongo abelii Cell differentiation protein RCD1 homolog(RQCD1) - CSB-YP728939PYX CSB-EP728939PYX CSB-BP728939PYX CSB-MP728939PYX from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Orangutan

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