FIG4
| Gene Symbol | FIG4 |
|---|---|
| Entrez Gene | 9896 |
| Alt Symbol | ALS11, BTOP, CMT4J, KIAA0274, SAC3, YVS, dJ249I4.1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | FIG4 phosphoinositide 5-phosphatase |
| Other Description | FIG4 homolog, SAC domain containing lipid phosphatase|FIG4 homolog, SAC1 domain containing lipid phosphatase|FIG4 homolog, SAC1 lipid phosphatase domain containing|SAC domain-containing protein 3|Sac domain-containing inositol phosphatase 3|phosphatidylinositol 3,5-bisphosphate 5-phosphatase|polyphosphoinositide phosphatase |
| Swissprots | Q53H49 Q92562 Q5TCS6 |
| Accessions | EAW48332 Q92562 AA815086 AA946705 AI476769 AK222732 BAD96452 AK291671 BAF84360 AK293422 BAG56929 BC041338 AAH41338 BM016965 BU683891 D87464 BAA13403 DA811740 XM_011536281 XP_011534583 NM_014845 NP_055660 |
| Function | The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide substrates in the order PtdIns(4,5)P2 > PtdIns(3,5)P2 > PtdIns(3,4,5)P3. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes. {ECO:0000269|PubMed:17556371}. |
| Subcellular Location | Endosome membrane {ECO:0000269|PubMed:17556371}. Note=Localization requires VAC14 and PIKFYVE. |
FIG4 (H-300) - sc-98633 from Santa Cruz Biotechnology
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Anti-FIG4 antibody - ab97621 from Abcam
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Anti-FIG4 antibody [S202-7] (HRP) - ab186301 from Abcam
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Anti-FIG4 antibody [S202-7] - C-terminal - ab186269 from Abcam
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Anti-FIG4 antibody [S202-7] - C-terminal (FITC) - ab186242 from Abcam
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Anti-FIG4 antibody [S2027] - C-terminal (Biotin) - ab186329 from Abcam
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Anti-FIG4 Antibody (aa688-907, clone S202-7, Atto 390) - LS-C229328 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, Atto 488) - LS-C229333 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, Atto 594) - LS-C229335 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, Atto 565) - LS-C229334 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, Atto 655) - LS-C229337 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, Atto 680) - LS-C229338 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, AP) - LS-C229340 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, Atto 633) - LS-C229336 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, Atto 700) - LS-C229339 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, Biotin) - LS-C230135 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, FITC) - LS-C230136 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, APC) - LS-C230133 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa846-874, APC) - LS-C257285 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, SA) - LS-C230141 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa846-874, AP) - LS-C257284 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, PE, Atto 594) - LS-C230138 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, RPE) - LS-C230140 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa688-907, clone S202-7, PerCP) - LS-C230139 from LifeSpan Bioscience
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Anti-FIG4 Antibody (aa846-874, Biotin) - LS-C257286 from LifeSpan Bioscience
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