FIG4

Gene Symbol	FIG4
Entrez Gene	9896
Alt Symbol	ALS11, BTOP, CMT4J, KIAA0274, SAC3, YVS, dJ249I4.1
Species	Human
Gene Type	protein-coding
Description	FIG4 phosphoinositide 5-phosphatase
Other Description	FIG4 homolog, SAC domain containing lipid phosphatase|FIG4 homolog, SAC1 domain containing lipid phosphatase|FIG4 homolog, SAC1 lipid phosphatase domain containing|SAC domain-containing protein 3|Sac domain-containing inositol phosphatase 3|phosphatidylinositol 3,5-bisphosphate 5-phosphatase|polyphosphoinositide phosphatase
Swissprots	Q53H49 Q92562 Q5TCS6
Accessions	EAW48332 Q92562 AA815086 AA946705 AI476769 AK222732 BAD96452 AK291671 BAF84360 AK293422 BAG56929 BC041338 AAH41338 BM016965 BU683891 D87464 BAA13403 DA811740 XM_011536281 XP_011534583 NM_014845 NP_055660
Function	The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide substrates in the order PtdIns(4,5)P2 > PtdIns(3,5)P2 > PtdIns(3,4,5)P3. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes. {ECO:0000269|PubMed:17556371}.
Subcellular Location	Endosome membrane {ECO:0000269|PubMed:17556371}. Note=Localization requires VAC14 and PIKFYVE.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FIG4 CRISPR/Cas9 KO Plasmid (h) - sc-404404 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

FIG4 HDR Plasmid (h) - sc-404404-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FIG4 Double Nickase Plasmid (h) - sc-404404-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FIG4 Double Nickase Plasmid (h2) - sc-404404-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FIG4 CRISPR Activation Plasmid (h) - sc-404404-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

FIG4 CRISPR Activation Plasmid (h2) - sc-404404-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

FIG4 Lentiviral Activation Particles (h) - sc-404404-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FIG4 Lentiviral Activation Particles (h2) - sc-404404-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FIG4 siRNA (h) - sc-72208 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

FIG4 shRNA Plasmid (h) - sc-72208-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

FIG4 shRNA (h) Lentiviral Particles - sc-72208-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® Human Phosphatase - SIHP0291 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0290 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0289 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN8692 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8692 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

FIG4 siRNA (Human) - CRH6641 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

FIG4 - MBS8230923 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

FIG4 CRISPR/Cas9 KO Plasmid (h2) - sc-404404-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

FIG4 HDR Plasmid (h2) - sc-404404-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human FIG4 (NM_014845.5) - SHH294989 from Creative biogene Category siRNA Species Reactivities Human

Human FIG4 siRNA - orb267143 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

FIG4 shRNA Plasmid (Human) - CHH6641 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

FIG4 miRNA 3'UTR clone - MiUTR3H-10578 from Creative biogene Species Reactivities Human

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