Gene Symbol |
Ndufs8
|
Entrez Gene |
225887
|
Alt Symbol |
BC021616, CI-23kD, TYKY
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
NADH dehydrogenase (ubiquinone) Fe-S protein 8
|
Other Description |
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial|NADH-ubiquinone oxidoreductase 23 kDa subunit|complex I-23kD
|
Swissprots |
Q8K3J1
|
Accessions |
AAM34451 EDL32969 EDL32970 Q8K3J1 AK135069 BAE22408 AK149674 BAE29018 AK153182 BAE31784 AK153900 BAE32243 AK164901 BAE37960 AK167907 BAE39914 BC021616 AAH21616 BC086766 AAH86766 BP775598 NM_001271443 NP_001258372 NM_001271444 NP_001258373 NM_144870 NP_659119
|
Function |
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
|
Subcellular Location |
Mitochondrion {ECO:0000250}.
|
Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|