| Gene Symbol | Ndufs8 |
|---|---|
| Entrez Gene | 225887 |
| Alt Symbol | BC021616, CI-23kD, TYKY |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | NADH dehydrogenase (ubiquinone) Fe-S protein 8 |
| Other Description | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial|NADH-ubiquinone oxidoreductase 23 kDa subunit|complex I-23kD |
| Swissprots | Q8K3J1 |
| Accessions | AAM34451 EDL32969 EDL32970 Q8K3J1 AK135069 BAE22408 AK149674 BAE29018 AK153182 BAE31784 AK153900 BAE32243 AK164901 BAE37960 AK167907 BAE39914 BC021616 AAH21616 BC086766 AAH86766 BP775598 NM_001271443 NP_001258372 NM_001271444 NP_001258373 NM_144870 NP_659119 |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}. |
| Subcellular Location | Mitochondrion {ECO:0000250}. |
| Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |