Gene Symbol | Ndufs8 |
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Entrez Gene | 225887 |
Alt Symbol | BC021616, CI-23kD, TYKY |
Species | Mouse |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) Fe-S protein 8 |
Other Description | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial|NADH-ubiquinone oxidoreductase 23 kDa subunit|complex I-23kD |
Swissprots | Q8K3J1 |
Accessions | AAM34451 EDL32969 EDL32970 Q8K3J1 AK135069 BAE22408 AK149674 BAE29018 AK153182 BAE31784 AK153900 BAE32243 AK164901 BAE37960 AK167907 BAE39914 BC021616 AAH21616 BC086766 AAH86766 BP775598 NM_001271443 NP_001258372 NM_001271444 NP_001258373 NM_144870 NP_659119 |
Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion {ECO:0000250}. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFS8 CRISPR/Cas9 KO Plasmid (m) - sc-432573 from Santa Cruz Biotechnology
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NDUFS8 HDR Plasmid (m) - sc-432573-HDR from Santa Cruz Biotechnology
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NDUFS8 Double Nickase Plasmid (m) - sc-432573-NIC from Santa Cruz Biotechnology
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NDUFS8 Double Nickase Plasmid (m2) - sc-432573-NIC-2 from Santa Cruz Biotechnology
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NDUFS8 CRISPR Activation Plasmid (m) - sc-432573-ACT from Santa Cruz Biotechnology
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NDUFS8 CRISPR Activation Plasmid (m2) - sc-432573-ACT-2 from Santa Cruz Biotechnology
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NDUFS8 Lentiviral Activation Particles (m) - sc-432573-LAC from Santa Cruz Biotechnology
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NDUFS8 Lentiviral Activation Particles (m2) - sc-432573-LAC-2 from Santa Cruz Biotechnology
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NDUFS8 siRNA (m) - sc-149890 from Santa Cruz Biotechnology
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NDUFS8 shRNA Plasmid (m) - sc-149890-SH from Santa Cruz Biotechnology
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NDUFS8 shRNA (m) Lentiviral Particles - sc-149890-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU040801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN36324 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36324 from Sigma-Aldrich
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NDUFS8 siRNA (Mouse) - CRN2461 from Cohesion Biosciences
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shRNA set against Mouse NDUFS8 (NM_144870.5) - SHH350924 from Creative biogene
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Mouse NDUFS8 siRNA - orb291936 from Biorbyt
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NDUFS8 shRNA Plasmid (Mouse) - CHN2461 from Cohesion Biosciences
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