MVB12A

Gene Symbol MVB12A
Entrez Gene 93343
Alt Symbol CFBP, FAM125A
Species Human
Gene Type protein-coding
Description multivesicular body subunit 12A
Other Description CIN85/CD2AP family binding protein|ESCRT-I complex subunit MVB12A|family with sequence similarity 125, member A
Swissprots Q96I18 Q96EY5
Accessions CAC38635 EAW84604 EAW84605 Q96EY5 AK057057 AK289487 BAF82176 BC007883 AAH07883 BC011840 AAH11840 BG684013 BP394542 BY996463 CD672349 DR006745 HG510441 HG510444 NM_001304547 NP_001291476 NM_138401 NP_612410
Function Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down- regulation of EGF receptor. {ECO:0000269|PubMed:16895919}.
Subcellular Location Cytoplasm. Nucleus. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Late endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Colocalizes with F-actin. Some fraction may be nuclear.
Tissue Specificity Ubiquitously expressed except in skeletal muscle. {ECO:0000269|PubMed:16895919}.
Top Pathways Endocytosis

MVB12A (G-14) - sc-242430 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MVB12A (N-20) - sc-242428 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-FAM125A antibody - ab130412 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab130412 at 1/50 dilution staining FAM125A in Paraffin-embedded Human colon tissue by Immunohistochemistry.

FAM125A Antibody - NBP1-91882 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FAM125A Antibody [NBP1-91882] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4

FAM125A Antibody - NBP1-91883 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MVB12A antibody produced in rabbit - HPA042231 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FAM125A: <B>Cat. No. HPA042231</B>: Immunohistochemical staining of human bronchus shows strong cytoplasmic and membranous positivity in respiratory epithelial cells.

FAM125A antibody - H00093343-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

Anti-MVB12A (aa 112-197) polyclonal antibody - DPABH-24495 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-MVB12A antibody produced in rabbit - HPA041885 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FAM125A: <B>Cat. No. HPA041885</B>: Immunohistochemical staining of human colon shows moderate cytoplasmic and membranous positivity in glandular cells.

FAM125A-Antibody-Center - AP22166c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-FAM125A Antibody (Center) at 1:2000 dilution Lane 1: U-2OS whole cell lysate Lane 2: U-251 MG whole cell lysate Lane 3: A431 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 29 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

FAM125A Antibody / CFBP (F53957) - F53957 from NSJ Bioreagent

Prices $125.00, $299.00
Sizes 50 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide), 200 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide)
Host Rabbit
Clonality Polyclonal
Western blot testing of human 1) U-2OS, 2) U-251 MG and 3) A431 cell lysate with FAM125A antibody at 1:2000. Predicted molecular weight: 29 kDa.

FAM125A antibody (FITC) - orb187842 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

FAM125A Antibody (N-Terminal Region) (F54126) - F54126 from NSJ Bioreagent

Prices $125.00, $299.00
Sizes 50 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide), 200 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide)
Host Rabbit
Clonality Polyclonal
Western blot testing of FAM125A antibody at 1:2000 + human PC-3 cell lysate. Predicted molecular weight ~29 kDa.

FAM125A-Antibody-N-Term - AP22249a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Anti-FAM125A Antibody (N-Term) at 1:2000 dilution + PC-3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 29 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Anti-FAM125A polyclonal antibody - CABT-BL1428 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

FAM125A, Polyclonal Antibody - MBS9217337 from MyBioSource

Prices $155.00, $340.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal

FAM125A, Polyclonal Antibody - MBS9231055 from MyBioSource

Prices $150.00, $340.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal

FAM125A antibody - center region (OAAB13462) - OAAB13462 from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

FAM125A antibody - 25816-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal
Jurkat cells were subjected to SDS PAGE followed by western blot with 25816-1-AP( FAM125A Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours
Search more