MVB12A

Gene Symbol	MVB12A
Entrez Gene	93343
Alt Symbol	CFBP, FAM125A
Species	Human
Gene Type	protein-coding
Description	multivesicular body subunit 12A
Other Description	CIN85/CD2AP family binding protein|ESCRT-I complex subunit MVB12A|family with sequence similarity 125, member A
Swissprots	Q96I18 Q96EY5
Accessions	CAC38635 EAW84604 EAW84605 Q96EY5 AK057057 AK289487 BAF82176 BC007883 AAH07883 BC011840 AAH11840 BG684013 BP394542 BY996463 CD672349 DR006745 HG510441 HG510444 NM_001304547 NP_001291476 NM_138401 NP_612410
Function	Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down- regulation of EGF receptor. {ECO:0000269|PubMed:16895919}.
Subcellular Location	Cytoplasm. Nucleus. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Late endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Colocalizes with F-actin. Some fraction may be nuclear.
Tissue Specificity	Ubiquitously expressed except in skeletal muscle. {ECO:0000269|PubMed:16895919}.
Top Pathways	Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FAM125A-Antibody-Center-Blocking-Peptide - BP18023c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FAM125A fusion protein - Ag23013 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET30a Species Human

Recombinant Human Multivesicular body subunit 12A(FAM125A) - CSB-YP846615HU CSB-EP846615HU CSB-BP846615HU CSB-MP846615HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FAM125A Protein - NBP1-91883PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

FAM125A Recombinant Protein Antigen - NBP1-91882PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FAM125A Peptide, Human - M34GP05251H from Creative Peptides Category Peptide Source Synthetic. Species Human

Multivesicular body subunit 12A (FAM125A), Recombinant Protein - MBS1334702 from MyBioSource Category Protein Prices $1,025.00, $1,025.00, $1,255.00, $1,255.00, $1,585.00, $1,585.00, $2,050.00, $2,050.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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