MVB12A

Gene Symbol MVB12A
Entrez Gene 93343
Alt Symbol CFBP, FAM125A
Species Human
Gene Type protein-coding
Description multivesicular body subunit 12A
Other Description CIN85/CD2AP family binding protein|ESCRT-I complex subunit MVB12A|family with sequence similarity 125, member A
Swissprots Q96I18 Q96EY5
Accessions CAC38635 EAW84604 EAW84605 Q96EY5 AK057057 AK289487 BAF82176 BC007883 AAH07883 BC011840 AAH11840 BG684013 BP394542 BY996463 CD672349 DR006745 HG510441 HG510444 NM_001304547 NP_001291476 NM_138401 NP_612410
Function Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down- regulation of EGF receptor. {ECO:0000269|PubMed:16895919}.
Subcellular Location Cytoplasm. Nucleus. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Late endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Colocalizes with F-actin. Some fraction may be nuclear.
Tissue Specificity Ubiquitously expressed except in skeletal muscle. {ECO:0000269|PubMed:16895919}.
Top Pathways Endocytosis

CFBP CRISPR/Cas9 KO Plasmid (h) - sc-409502 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CFBP HDR Plasmid (h) - sc-409502-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CFBP Double Nickase Plasmid (h) - sc-409502-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CFBP Double Nickase Plasmid (h2) - sc-409502-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CFBP CRISPR Activation Plasmid (h) - sc-409502-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CFBP CRISPR Activation Plasmid (h2) - sc-409502-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CFBP Lentiviral Activation Particles (h) - sc-409502-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CFBP Lentiviral Activation Particles (h2) - sc-409502-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MVB12A siRNA (h) - sc-97374 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MVB12A shRNA Plasmid (h) - sc-97374-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MVB12A shRNA (h) Lentiviral Particles - sc-97374-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU018641 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8154 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8154 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03152 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03152

MVB12A siRNA (Human) - CRJ4202 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FAM125A (NM_138401.2) - SHH289421 from Creative biogene

Category siRNA
Species Reactivities Human

Human MVB12A siRNA - orb274703 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MVB12A shRNA Plasmid (Human) - CHJ4202 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FAM125A miRNA 3'UTR clone - MiUTR1H-03412 from Creative biogene

Species Reactivities Human
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