| Gene Symbol |
RIC8B
|
| Entrez Gene |
55188
|
| Alt Symbol |
RIC8, hSyn
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RIC8 guanine nucleotide exchange factor B
|
| Other Description |
brain synembrin|brain synembryn|resistance to inhibitors of cholinesterase 8 homolog B|synembryn-B
|
| Swissprots |
Q4G103 A2RTZ0 Q86WD3 Q6ZRN4 Q9NVN3
|
| Accessions |
CAE89453 EAW97785 EAW97786 EAW97787 Q9NVN3 AK001482 BAA91717 AK128102 AY221116 AAO65923 BC034220 AAH34220 BC132689 AAI32690 BC144056 AAI44057 CB215722 DA118965 DA325821 DA534432 XM_005268998 XP_005269055 XM_011538526 XP_011536828 XM_011538527 XP_011536829 XM_011538528 XP_011536830 XM_011538529 XP_011536831 XR_245940 XR_944604 XR_944605 XR_944606 XR_944607 XR_944608 NM_018157 NP_060627
|
| Function |
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cell cortex {ECO:0000269|PubMed:12652642}. Note=Localizes to the cell cortex.
|