Gene Symbol | RIC8B |
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Entrez Gene | 55188 |
Alt Symbol | RIC8, hSyn |
Species | Human |
Gene Type | protein-coding |
Description | RIC8 guanine nucleotide exchange factor B |
Other Description | brain synembrin|brain synembryn|resistance to inhibitors of cholinesterase 8 homolog B|synembryn-B |
Swissprots | Q4G103 A2RTZ0 Q86WD3 Q6ZRN4 Q9NVN3 |
Accessions | CAE89453 EAW97785 EAW97786 EAW97787 Q9NVN3 AK001482 BAA91717 AK128102 AY221116 AAO65923 BC034220 AAH34220 BC132689 AAI32690 BC144056 AAI44057 CB215722 DA118965 DA325821 DA534432 XM_005268998 XP_005269055 XM_011538526 XP_011536828 XM_011538527 XP_011536829 XM_011538528 XP_011536830 XM_011538529 XP_011536831 XR_245940 XR_944604 XR_944605 XR_944606 XR_944607 XR_944608 NM_018157 NP_060627 |
Function | Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction. {ECO:0000250}. |
Subcellular Location | Cytoplasm, cell cortex {ECO:0000269|PubMed:12652642}. Note=Localizes to the cell cortex. |
RIC8 peptide - ab45642 from Abcam
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RIC8B Antibody Blocking Peptide - LS-E20833 from LifeSpan Bioscience
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RIC8B Antibody Blocking Peptide - LS-E20834 from LifeSpan Bioscience
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RIC8B Blocking Peptide - 33R-4361 from Fitzgerald
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RIC8B Blocking Peptide - 33R-3821 from Fitzgerald
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RIC8B fusion protein - Ag11888 from Proteintech Group
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RIC8B fusion protein - Ag12154 from Proteintech Group
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Recombinant Human RIC8B, GST-tagged - RIC8B-2302H from Creative Biomart
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Recombinant Human Synembryn-B(RIC8B) - CSB-YP889121HU CSB-EP889121HU CSB-BP889121HU CSB-MP889121HU from Cusabio
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Synembryn-B / RIC8B - TP314610 from Acris Antibodies
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RIC8B Protein - NBP2-13232PEP from Novus Biologicals
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RIC8B Peptide, Human - M34GP13297H from Creative Peptides
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Synembryn-B (RIC8B), Recombinant Protein - MBS1456987 from MyBioSource
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