CABIN1

Gene Symbol CABIN1
Entrez Gene 23523
Alt Symbol CAIN, PPP3IN
Species Human
Gene Type protein-coding
Description calcineurin binding protein 1
Other Description calcineurin binding protein cabin 1|calcineurin inhibitor|calcineurin-binding protein cabin-1
Swissprots Q9Y6J0 Q6PHY0 G5E9F3 Q9Y460
Accessions CAB62954 EAW59637 EAW59638 EAW59639 EAW59640 Q9Y6J0 AB002328 BAA20788 AF072441 AAD40846 AK127950 AK307522 AL390166 CAB99097 AL703593 BC013099 BC021929 AAH21929 BC028969 AAH28969 BC041659 AAH41659 BC054497 AAH54497 HG512085 XM_005261415 XP_005261472 XM_005261416 XP_005261473 XM_005261417 XP_005261474 XM_005261419 XP_005261476 XM_005261420 XP_005261477 XM_006724179 XP_006724242 XM_006724180 XP_006724243 XM_006724181 XP_006724244 XM_006724182 XP_006724245 XM_006724184 XP_006724247 XM_011530026 XP_011528328 XM_011530027 XP_011528329 XM_011530028 XP_011528330 XM_011530029 XP_011528331 XM_011530030 XP_011528332 XM_011530031 XP_011528333 XM_011530032 XP_011528334 XM_011530033 XP_011528335 NM_001199281 NP_001186210 NM_001201429 NP_001188358 NM_012295 NP_036427
Function May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes. {ECO:0000269|PubMed:14718166, ECO:0000269|PubMed:9655484}.
Subcellular Location Nucleus {ECO:0000269|PubMed:9655484}.
Tissue Specificity Widely expressed in different tissues. {ECO:0000269|PubMed:9655484}.

CABIN1 (D2B9F) Rabbit mAb - 12660 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2B9F
Western blot analysis of extracts from various cell lines using CABIN1 (D2B9F) Rabbit mAb.

Cabin-1 (B-11) - sc-514269 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cabin-1 (B-11): sc-514269. Western blot analysis of Cabin-1 expression in TE671 (A) and IMR-32 (B) whole cell lysates.

Cabin-1 (E-11) - sc-514250 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cabin-1 (E-11): sc-514250. Western blot analysis of Cabin-1 expression in SK-N-SH (A) and Jurkat (B) whole cell lysates and HeLa nuclear extract (C).

Cabin-1 (K-14) - sc-12519 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Cabin-1 (K-14): sc-12519. Western blot analysis of Cabin-1 expression in HeLa nuclear extract.

Cabin-1 (N-19) - sc-8745 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Cabin-1 (N-19): sc-8745. Immunoperoxidase staining of formalin fixed, paraffin-embedded human rectum tissue showing cytoplasmic and nuclear staining of glandular cells and interstitial cells.

Cabin-1 (H-300) - sc-367032 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-CAIN antibody - ab76600 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CAIN antibody (ab76600) at 1 µg/mlLane 1 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell Lysate Lane 2 : SK N SH (Human neuroblastoma) Whole Cell Lysate Lane 3 : Skeletal Muscle (Mouse) Tissue LysateLane 4 : TE 671 (Human Rhabdomyosarcoma) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CAIN antibody - ab200673 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CAIN antibody (ab200673)Lane 1 : HEK293T whole cell lysateLane 2 : PC12 whole cell lysate

Anti-CABIN1 Antibody (aa1-111) - LS-C306685 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

CAIN Antibody - NBP1-91745 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: CAIN Antibody [NBP1-91745] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.

CAIN Antibody (2G2) - H00023523-M01A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 2G2

CAIN Antibody (2F5) - H00023523-M02A-200ul from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 2F5

CAIN Antibody - H00023523-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Monoclonal Anti-CABIN1 antibody produced in mouse - SAB1412818 from Sigma-Aldrich

Prices $347.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 2F5
<B>Immunoblotting</B><BR/>Anti-CABIN1:<B>Cat. No. SAB1412818</B>: Antibody concentration: 1 μg/mL. Immunofluorescence band of ~37.8 kDa using immunogen protein lysate.

Monoclonal Anti-CABIN1 antibody produced in mouse - WH0023523M1 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2G2
<B>Immunoblotting</B><BR/>Monoclonal Anti-CABIN1, <B>Cat. No. WH0023523M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~38.21 kDa using immunogen protein lysate.

Monoclonal Anti-CABIN1, (N-terminal) antibody produced in mouse - SAB1404977 from Sigma-Aldrich

Prices $347.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 2G2
<B>Immunoblotting</B><BR/>Monoclonal Anti-CABIN1: <B>Cat. No. SAB1404977</B>: Antibody concentration: 1 μg/mL. Specific band of ~38.2 kDa using immunogen protein lysate.

Anti-CABIN1 antibody produced in rabbit - HPA043296 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CABIN1: <B>Cat. No. HPA043296</B>: Immunohistochemical staining of human rectum shows strong nuclear and cytoplasmic positivity in glandular cells.

NUP214 antibody - GTX23349 from GeneTex

Prices $319.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal

Anti -CABIN1 (Calcineurin Binding Protein CABIN1) - 137418 from USBiological Life Science

Host Rabbit
Clonality Monoclonal
Clone 13G22

Anti -CABIN1 (Calcineurin-binding Protein Cabin-1, Calcineurin Inhibitor, CAIN, KIAA0330) - 124200 from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 2G2

Anti -CABIN1 (Calcineurin-binding Protein Cabin-1, Calcineurin Inhibitor, CAIN, KIAA0330)(AP) - 124200-AP from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 2G2

Anti -CABIN1 (Calcineurin-binding Protein Cabin-1, Calcineurin Inhibitor, CAIN, KIAA0330)(FITC) - 124200-FITC from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 2G2

Anti -CABIN1 (Calcineurin-binding Protein Cabin-1, Calcineurin Inhibitor, CAIN, KIAA0330)(HRP) - 124200-HRP from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 2G2

Anti -CABIN1 (Calcineurin-binding Protein Cabin-1, Calcineurin Inhibitor, CAIN, KIAA0330)(PE) - 124200-PE from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 2G2
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