UBQLN1

Gene Symbol UBQLN1
Entrez Gene 29979
Alt Symbol DA41, DSK2, PLIC-1, UBQN, XDRP1
Species Human
Gene Type protein-coding
Description ubiquilin 1
Other Description hPLIC-1|protein linking IAP with cytoskeleton 1|ubiquilin-1
Swissprots Q9HAZ5 Q8IXS9 Q8N2Q3 Q5T6J5 Q9UMX0 Q9H0T8 Q5T6J9 Q9H3R4
Accessions EAW62658 EAW62659 EAW62660 EAW62661 EAW62662 EAW62663 EAW62664 Q9UMX0 AB035275 BAB20436 AB209468 BAD92705 AF176069 AAD49751 AF293384 AAG02473 AK027556 BAG51344 AK027576 BAG51350 AK074535 AK125815 AL136643 CAB66578 BC010066 AAH10066 BC039294 AAH39294 DA317805 XM_005251948 XP_005252005 NM_013438 NP_038466 NM_053067 NP_444295
Function Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors. Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:23979357}. Nucleus {ECO:0000269|PubMed:23979357}. Note=Detected in neuronal processes and at synapses (By similarity). Detected in cytosolic puncta that may correspond to autophagosomes. {ECO:0000250}.
Tissue Specificity Ubiquitous. Highly expressed throughout the brain; detected in neurons and in neuropathological lesions, such as neurofibrillary tangles and Lewy bodies. Highly expressed in heart, placenta, pancreas, lung, liver, skeletal muscle and kidney. {ECO:0000269|PubMed:11076969, ECO:0000269|PubMed:11853878}.
Top Pathways Protein processing in endoplasmic reticulum

UBQLN1 (D3T7F) Rabbit mAb - 14526 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3T7F
Western blot analysis of extracts from various cell lines using UBQLN1 (D3T7F) Rabbit mAb.

PLIC-1 (C-16) - sc-14653 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PLIC-1 (C-16): sc-14653. Western blot analysis of PLIC-1 expression in HEK293 (A), Daoy (B) and K-562 (C) whole cell lysates.

PLIC-1 (H-20) - sc-14652 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PLIC-1 (H-20): sc-14652. Western blot analysis of PLIC-1 expression in IMR-32 whole cell lysate.

Anti-Ubiquilin antibody - ab3341 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Ubiquilin antibody - ab96870 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-Ubiquilin antibody (ab96870) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-Ubiquilin antibody - ab128011 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab128011, at a concentration of 10 µg/ml, staining Ubiquilin in paraffin-embedded Human tonsil tissue by Immunohistochemistry.

Anti-Ubiquilin antibody - ab197176 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-Ubiquilin antibody (ab197176) at 1/500 dilution + Human fetal brain lysate

Anti-UBQLN1 / Ubiquilin Antibody (AP) - LS-C226601 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (Internal, clone 3D5E2) IHC-plus™ - LS-B3142 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3D5E2
Anti-UBQLN1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3142 concentration 10 ug/ml.

Anti-UBQLN1 / Ubiquilin Antibody (aa290-339) IHC-plus™ - LS-B3574 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-UBQLN1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3574 concentration 5 ug/ml.

Anti-UBQLN1 / Ubiquilin Antibody (C-Terminus) - LS-C40072 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-UBQLN1 / Ubiquilin Antibody (aa2-18) - LS-C93224 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (N-Terminus, AP) - LS-C226595 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (N-Terminus, APC) - LS-C226596 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (N-Terminus, Biotin) - LS-C226597 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (N-Terminus, FITC) - LS-C226599 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (N-Terminus, Azide-free, HRP) - LS-C226598 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (N-Terminus, PE) - LS-C226600 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (APC) - LS-C226602 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (Biotin) - LS-C226603 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (Azide-free, HRP) - LS-C226604 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (PE) - LS-C226606 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (N-Terminus, AP) - LS-C226607 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (N-Terminus, Biotin) - LS-C226608 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBQLN1 / Ubiquilin Antibody (FITC) - LS-C226605 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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