UBQLN1

Gene Symbol	UBQLN1
Entrez Gene	29979
Alt Symbol	DA41, DSK2, PLIC-1, UBQN, XDRP1
Species	Human
Gene Type	protein-coding
Description	ubiquilin 1
Other Description	hPLIC-1|protein linking IAP with cytoskeleton 1|ubiquilin-1
Swissprots	Q9HAZ5 Q8IXS9 Q8N2Q3 Q5T6J5 Q9UMX0 Q9H0T8 Q5T6J9 Q9H3R4
Accessions	EAW62658 EAW62659 EAW62660 EAW62661 EAW62662 EAW62663 EAW62664 Q9UMX0 AB035275 BAB20436 AB209468 BAD92705 AF176069 AAD49751 AF293384 AAG02473 AK027556 BAG51344 AK027576 BAG51350 AK074535 AK125815 AL136643 CAB66578 BC010066 AAH10066 BC039294 AAH39294 DA317805 XM_005251948 XP_005252005 NM_013438 NP_038466 NM_053067 NP_444295
Function	Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors. Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:23979357}. Nucleus {ECO:0000269|PubMed:23979357}. Note=Detected in neuronal processes and at synapses (By similarity). Detected in cytosolic puncta that may correspond to autophagosomes. {ECO:0000250}.
Tissue Specificity	Ubiquitous. Highly expressed throughout the brain; detected in neurons and in neuropathological lesions, such as neurofibrillary tangles and Lewy bodies. Highly expressed in heart, placenta, pancreas, lung, liver, skeletal muscle and kidney. {ECO:0000269|PubMed:11076969, ECO:0000269|PubMed:11853878}.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Ubiquilin full length protein - ab153310 from Abcam Category Protein Source Wheat germ Species Human

UBQLN1 / Ubiquilin Antibody Blocking Peptide - LS-E6918 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UBQLN1 / Ubiquilin Antibody Blocking Peptide - LS-E6919 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UBQLN1 / Ubiquilin Antibody Blocking Peptide - LS-E6922 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UBQLN1 / Ubiquilin Antibody Blocking Peptide - LS-E19827 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Ubiquilin 1 Protein - H00029979-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Ubiquilin 1 Peptide - P1006 from Novus Biologicals Category Peptide Species Human

Ubiquilin 1 Peptide - P1005 from Novus Biologicals Category Peptide Species Human

Ubiquilin 1 Peptide - P0999 from Novus Biologicals Category Peptide Species Human

Ubiquilin1-PLIC1-Antibody-C-term-Blocking-peptide - BP2179c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Ubiquilin1-PLIC1-Antibody-N-term-Blocking-peptide - BP2179a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Ubiquilin1-Antibody-Center-Blocking-Peptide - BP2176c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Ubiquilin1-Antibody-N-term-Blocking-Peptide - BP2176a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Ubiquilin 1 Tandem UBA (TUBE2) Agarose, CF - AM-130-250 from R&D Systems Category Protein Source E. coli-derived,

Recombinant Human Ubiquilin 1 Tandem UBA (TUBE2) Biotin, CF - UBE-115-250 from R&D Systems Category Protein

Recombinant Human His6-Ubiquilin 1 Tandem UBA (TUBE2), CF - UBE-110-250 from R&D Systems Category Protein

Ubiquilin 1 Blocking Peptide - 33R-7544 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Ubiquilin-1 (UBQLN1) - H00029979-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Ubiquilin-1 (UBQLN1) - H00029979-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Ubiquilin 1 fusion protein - Ag20252 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Ubiquilin 1 fusion protein - Ag17530 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Ubiquilin 1 fusion protein - Ag17659 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human UBQLN1, GST-tagged - UBQLN1-3558H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Ubiquilin-1(UBQLN1) - CSB-YP892477HU CSB-EP892477HU CSB-BP892477HU CSB-MP892477HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human His6-Ubiquilin 1 Tandem UBA (TUBE2), CF - UBE-110 from R&D Systems Category Protein Prices $245.00 Sizes 250 µg Species Human

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