UBQLN1

Gene Symbol UBQLN1
Entrez Gene 29979
Alt Symbol DA41, DSK2, PLIC-1, UBQN, XDRP1
Species Human
Gene Type protein-coding
Description ubiquilin 1
Other Description hPLIC-1|protein linking IAP with cytoskeleton 1|ubiquilin-1
Swissprots Q9HAZ5 Q8IXS9 Q8N2Q3 Q5T6J5 Q9UMX0 Q9H0T8 Q5T6J9 Q9H3R4
Accessions EAW62658 EAW62659 EAW62660 EAW62661 EAW62662 EAW62663 EAW62664 Q9UMX0 AB035275 BAB20436 AB209468 BAD92705 AF176069 AAD49751 AF293384 AAG02473 AK027556 BAG51344 AK027576 BAG51350 AK074535 AK125815 AL136643 CAB66578 BC010066 AAH10066 BC039294 AAH39294 DA317805 XM_005251948 XP_005252005 NM_013438 NP_038466 NM_053067 NP_444295
Function Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors. Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:23979357}. Nucleus {ECO:0000269|PubMed:23979357}. Note=Detected in neuronal processes and at synapses (By similarity). Detected in cytosolic puncta that may correspond to autophagosomes. {ECO:0000250}.
Tissue Specificity Ubiquitous. Highly expressed throughout the brain; detected in neurons and in neuropathological lesions, such as neurofibrillary tangles and Lewy bodies. Highly expressed in heart, placenta, pancreas, lung, liver, skeletal muscle and kidney. {ECO:0000269|PubMed:11076969, ECO:0000269|PubMed:11853878}.
Top Pathways Protein processing in endoplasmic reticulum

PLIC-1 CRISPR/Cas9 KO Plasmid (h) - sc-408872 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLIC-1 HDR Plasmid (h) - sc-408872-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLIC-1 Double Nickase Plasmid (h) - sc-408872-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLIC-1 Double Nickase Plasmid (h2) - sc-408872-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLIC-1 CRISPR Activation Plasmid (h) - sc-408872-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLIC-1 CRISPR Activation Plasmid (h2) - sc-408872-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLIC-1 Lentiviral Activation Particles (h) - sc-408872-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLIC-1 Lentiviral Activation Particles (h2) - sc-408872-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLIC-1 siRNA (h) - sc-41669 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLIC-1 shRNA Plasmid (h) - sc-41669-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLIC-1 shRNA (h) Lentiviral Particles - sc-41669-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ubiquilin 1 RNAi - H00029979-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Ubiquilin 1 RNAi - H00029979-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU084751 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1320 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1320 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10676 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10676

UBQLN1 siRNA (Human) - CRH9311 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UBQLN1 - MBS8224689 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human UBQLN1 (NM_013438.4) - SHH439456 from Creative biogene

Category siRNA
Species Reactivities Human

UBQLN1 shRNA Plasmid (Human) - CHH9311 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

UBQLN1 miRNA 3'UTR clone - MiUTR3H-07320 from Creative biogene

Species Reactivities Human

UBQLN1 miRNA 3'UTR clone - MiUTR3H-07321 from Creative biogene

Species Reactivities Human
Search more