Gene Symbol | ATP5J |
---|---|
Entrez Gene | 522 |
Alt Symbol | ATP5, ATP5A, ATPM, CF6, F6 |
Species | Human |
Gene Type | protein-coding |
Description | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 |
Other Description | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6|ATP synthase-coupling factor 6, mitochondrial|ATPase subunit F6|coupling factor 6|mitochondrial ATP synthase, coupling factor 6|mitochondrial ATP synthase, subunit F6|mitochondrial ATPase coupling factor 6|proliferation-inducing protein 36 |
Swissprots | J3KQ83 P18859 |
Accessions | CAE94071 EAX09970 EAX09971 EAX09972 EAX09973 EAX09974 EAX09975 P18859 AI085837 AK311899 BAG34840 AL110183 CAB53667 AY544129 AAT11160 BC001178 AAH01178 BC066310 AAH66310 BG938438 BI093033 BQ268216 BT007244 AAP35908 BU174560 CR456950 CAG33231 M37104 AAA51807 M73031 AAA58630 XM_005260992 XP_005261049 NM_001003696 NP_001003696 NM_001003697 NP_001003697 NM_001003701 NP_001003701 NM_001003703 NP_001003703 NM_001685 NP_001676 |
Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes. |
Subcellular Location | Mitochondrion. Mitochondrion inner membrane. |
Top Pathways | Alzheimer's disease, Huntington's disease, Oxidative phosphorylation |
Human ATP5J full length protein - ab152213 from Abcam
|
||||||||||
Human ATP5J full length protein - ab152214 from Abcam
|
||||||||||
Human ATP5J protein fragment - ab152215 from Abcam
|
||||||||||
ATP5J Antibody Blocking Peptide - LS-E1689 from LifeSpan Bioscience
|
||||||||||
Recombinant Human ATP5J Protein - H00000522-P01 from Novus Biologicals
|
||||||||||
Recombinant Human ATP5J Protein - H00000522-Q01 from Novus Biologicals
|
||||||||||
Recombinant Human ATP5J Protein - H00000522-P02 from Novus Biologicals
|
||||||||||
ATP5J-Antibody-Center-Blocking-peptide - BP12457c from Abgent, a WuXi AppTec company
|
||||||||||
ATPase subunit F6 - H00000522-P01-10 from Acris Antibodies
|
||||||||||
ATPase subunit F6 - H00000522-P01-25 from Acris Antibodies
|
||||||||||
ATPase subunit F6 - H00000522-P02 from Acris Antibodies
|
||||||||||
ATPase subunit F6 - H00000522-P02-10 from Acris Antibodies
|
||||||||||
ATPase subunit F6 - H00000522-P02-25 from Acris Antibodies
|
||||||||||
ATPase subunit F6 - H00000522-Q01-10 from Acris Antibodies
|
||||||||||
ATPase subunit F6 - H00000522-Q01-25 from Acris Antibodies
|
||||||||||
ATP5J fusion protein - Ag5263 from Proteintech Group
|
||||||||||
Recombinant Human ATP5J, GST-tagged - ATP5J-10025H from Creative Biomart
|
||||||||||
Recombinant Coupling Factor 6 (CF6) - RPQ185Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Coupling Factor 6 (CF6) - RPQ185Ra01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Coupling Factor 6 (CF6) - RPQ185Hu01 from Cloud-clone
|
||||||||||
Recombinant Vaccinia virus Protein F12 (F12L, F6) ,partial - CSB-YP329948VAD CSB-EP329948VAD CSB-BP329948VAD CSB-MP329948VAD from Cusabio
|
||||||||||
Recombinant Human ATP synthase-coupling factor 6, mitochondrial(ATP5J) - CSB-YP002369HU CSB-EP002369HU CSB-BP002369HU CSB-MP002369HU from Cusabio
|
||||||||||
ATPase subunit F6 (transcript variant 2) - TP300691 from Acris Antibodies
|
||||||||||
ATPase subunit F6 (transcript variant 3) - TP309756 from Acris Antibodies
|
||||||||||
ATP synthase-coupling factor 6, mitochondrial(ATP5J) , Recombinant Protein - MBS1403560 from MyBioSource
|