Gene Symbol | ATP5J |
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Entrez Gene | 522 |
Alt Symbol | ATP5, ATP5A, ATPM, CF6, F6 |
Species | Human |
Gene Type | protein-coding |
Description | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 |
Other Description | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6|ATP synthase-coupling factor 6, mitochondrial|ATPase subunit F6|coupling factor 6|mitochondrial ATP synthase, coupling factor 6|mitochondrial ATP synthase, subunit F6|mitochondrial ATPase coupling factor 6|proliferation-inducing protein 36 |
Swissprots | J3KQ83 P18859 |
Accessions | CAE94071 EAX09970 EAX09971 EAX09972 EAX09973 EAX09974 EAX09975 P18859 AI085837 AK311899 BAG34840 AL110183 CAB53667 AY544129 AAT11160 BC001178 AAH01178 BC066310 AAH66310 BG938438 BI093033 BQ268216 BT007244 AAP35908 BU174560 CR456950 CAG33231 M37104 AAA51807 M73031 AAA58630 XM_005260992 XP_005261049 NM_001003696 NP_001003696 NM_001003697 NP_001003697 NM_001003701 NP_001003701 NM_001003703 NP_001003703 NM_001685 NP_001676 |
Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes. |
Subcellular Location | Mitochondrion. Mitochondrion inner membrane. |
Top Pathways | Alzheimer's disease, Huntington's disease, Oxidative phosphorylation |
ATP5J (C-18) - sc-83192 from Santa Cruz Biotechnology
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Anti-ATP5J antibody - ab65841 from Abcam
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Anti-ATP5J antibody - ab154578 from Abcam
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Anti-ATP5J antibody [10C6AC9] - ab110279 from Abcam
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Anti-ATP5J Antibody - LS-C121393 from LifeSpan Bioscience
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Anti-ATP5J Antibody (Internal, Sepharose) - LS-C171666 from LifeSpan Bioscience
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Anti-ATP5J Antibody (Internal, Magnetic beads) - LS-C171665 from LifeSpan Bioscience
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Anti-ATP5J Antibody - LS-C190493 from LifeSpan Bioscience
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Anti-ATP5J Antibody (aa27-56) - LS-C319696 from LifeSpan Bioscience
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Anti-ATP5J Antibody (clone 1F10) - LS-C196720 from LifeSpan Bioscience
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Anti-ATP5J Antibody (Internal) - LS-C171664 from LifeSpan Bioscience
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Anti-ATP5J Antibody (aa27-56) - LS-C156660 from LifeSpan Bioscience
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ATP5J Antibody - NBP1-88888 from Novus Biologicals
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ATP5J Antibody - NBP2-15514 from Novus Biologicals
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ATP5J Antibody - NBP1-41445 from Novus Biologicals
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ATP5J Antibody (1F2) - H00000522-M09 from Novus Biologicals
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ATP5J Antibody (2F4) - H00000522-M02 from Novus Biologicals
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ATP5J Antibody (1F10) - H00000522-M01 from Novus Biologicals
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ATP5J Antibody - H00000522-A01 from Novus Biologicals
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Rabbit Anti-ATP5A Polyclonal Antibody - bs-2435R from Bioss
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Monoclonal Anti-ATP5J antibody produced in mouse - SAB1402124 from Sigma-Aldrich
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Anti-ATP5J antibody produced in rabbit - HPA031069 from Sigma-Aldrich
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Monoclonal Anti-ATP5J antibody produced in mouse - SAB1403589 from Sigma-Aldrich
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ATP5J-Antibody-Center - AP12457c from Abgent, a WuXi AppTec company
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ATP5J antibody - GTX110996 from GeneTex
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