| Gene Symbol |
CYP11B2
|
| Entrez Gene |
1585
|
| Alt Symbol |
ALDOS, CPN2, CYP11B, CYP11BL, CYPXIB2, P-450C18, P450C18, P450aldo
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 11, subfamily B, polypeptide 2
|
| Other Description |
aldosterone synthase|aldosterone-synthesizing enzyme|cytochrome P-450Aldo|cytochrome P-450C18|cytochrome P450 11B2, mitochondrial|cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2|mitochondrial cytochrome P450, family 11, subfamily B, polypeptide 2|steroid 11-beta-monooxygenase|steroid 11-beta/18-hydroxylase|steroid 18-hydroxylase, aldosterone synthase, P450C18, P450aldo
|
| Swissprots |
Q16726 P19099 B0ZBE4
|
| Accessions |
AAA35741 AAB34642 AAB34643 ACA05912 BAA01040 BAA02899 EAW82292 P19099 BC111458 AAI11459 X54741 CAA38539 XM_011516877 XP_011515179 XM_011516878 XP_011515180 XM_011516879 XP_011515181 NM_000498 NP_000489
|
| Function |
Preferentially catalyzes the conversion of 11- deoxycorticosterone to aldosterone via corticosterone and 18- hydroxycorticosterone. {ECO:0000269|PubMed:23322723}.
|
| Subcellular Location |
Mitochondrion membrane.
|
| Top Pathways |
Steroid hormone biosynthesis
|
![Western Blot: CYP11B2 Overexpression Lysate (Adult Normal) [NBL1-09672] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CYP11B2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2171_CYP11B2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09672-img0002.jpg)