Gene Symbol | Tfec |
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Entrez Gene | 21426 |
Alt Symbol | BB107417, Tcfec, bHLHe34 |
Species | Mouse |
Gene Type | protein-coding |
Description | transcription factor EC |
Other Description | TFE-C|mTFEC |
Swissprots | Q3TWR7 Q9WTW4 |
Accessions | EDL13894 EDL13895 Q9WTW4 AF077742 AAD24426 AK137141 BAE23248 AK156327 BAE33676 AK157426 BAE34087 AK159579 BAE35199 BC052832 BC064770 BC098494 AAH98494 XM_006505035 XP_006505098 XM_006505036 XP_006505099 XM_006505037 XP_006505100 XM_011241053 XP_011239355 NM_031198 NP_112475 |
Function | Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence) (By similarity). Binds to element F in an E-box sequence-specific manner (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form. {ECO:0000250, ECO:0000269|PubMed:11818452}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}. |
Tissue Specificity | Expressed in osteoclast-like cells (at protein level). Expressed in cells of the mononuclear phagocyte lineage. Expressed in macrophages and in osteoclast-like cells. {ECO:0000269|PubMed:9973413}. |
TFEC (P-15) - sc-11015 from Santa Cruz Biotechnology
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Tcfec Antibody (OAEB00520) - OAEB00520 from Aviva Systems Biology
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TFEC antibody - AP08822PU-N from Acris Antibodies
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Anti-TFEC Antibody - AC21-1242 from Abcore
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Anti-TFEC Antibody (AMCA) - AC21-1242-01 from Abcore
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Anti-TFEC Antibody (AP) - AC21-1242-02 from Abcore
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Anti-TFEC Antibody (APC) - AC21-1242-03 from Abcore
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Anti-TFEC Antibody (APC-Cy5.5) - AC21-1242-04 from Abcore
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Anti-TFEC Antibody (APC-Cy7) - AC21-1242-05 from Abcore
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Anti-TFEC Antibody (Avidin) - AC21-1242-06 from Abcore
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Anti-TFEC Antibody (Biotin) - AC21-1242-07 from Abcore
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Anti-TFEC Antibody (BPE) - AC21-1242-08 from Abcore
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Anti-TFEC Antibody (Cy3) - AC21-1242-09 from Abcore
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Anti-TFEC Antibody (Cy5) - AC21-1242-10 from Abcore
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Anti-TFEC Antibody (Cy5.5) - AC21-1242-11 from Abcore
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Anti-TFEC Antibody (FITC) - AC21-1242-12 from Abcore
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Anti-TFEC Antibody (Glucose Oxidase) - AC21-1242-13 from Abcore
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Anti-TFEC Antibody (HRP) - AC21-1242-14 from Abcore
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Anti-TFEC Antibody (PE-Cy5) - AC21-1242-15 from Abcore
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Anti-TFEC Antibody (PE-Cy5.5) - AC21-1242-16 from Abcore
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Anti-TFEC Antibody (PE-Cy7) - AC21-1242-17 from Abcore
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Anti-TFEC Antibody (PerCP) - AC21-1242-18 from Abcore
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Anti-TFEC Antibody (PerCP-Cy5.5) - AC21-1242-19 from Abcore
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Anti-TFEC Antibody (Rhodamine) - AC21-1242-20 from Abcore
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Anti-TFEC Antibody (RPE) - AC21-1242-21 from Abcore
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