Tfec

Gene Symbol Tfec
Entrez Gene 21426
Alt Symbol BB107417, Tcfec, bHLHe34
Species Mouse
Gene Type protein-coding
Description transcription factor EC
Other Description TFE-C|mTFEC
Swissprots Q3TWR7 Q9WTW4
Accessions EDL13894 EDL13895 Q9WTW4 AF077742 AAD24426 AK137141 BAE23248 AK156327 BAE33676 AK157426 BAE34087 AK159579 BAE35199 BC052832 BC064770 BC098494 AAH98494 XM_006505035 XP_006505098 XM_006505036 XP_006505099 XM_006505037 XP_006505100 XM_011241053 XP_011239355 NM_031198 NP_112475
Function Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence) (By similarity). Binds to element F in an E-box sequence-specific manner (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form. {ECO:0000250, ECO:0000269|PubMed:11818452}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.
Tissue Specificity Expressed in osteoclast-like cells (at protein level). Expressed in cells of the mononuclear phagocyte lineage. Expressed in macrophages and in osteoclast-like cells. {ECO:0000269|PubMed:9973413}.

TFEC siRNA (m) - sc-38512 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

TFEC shRNA Plasmid (m) - sc-38512-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

TFEC shRNA (m) Lentiviral Particles - sc-38512-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN42637 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42637 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TFEC siRNA (Mouse) - CRM4062 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

TFEC - MBS828864 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse Tcfec (NM_031198.3) - SHH424916 from Creative biogene

Category siRNA
Species Reactivities Mouse

TFEC shRNA Plasmid (Mouse) - CHM4062 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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