ERC1

Gene Symbol ERC1
Entrez Gene 23085
Alt Symbol Cast2, ELKS, ERC-1, RAB6IP2
Species Human
Gene Type protein-coding
Description ELKS/RAB6-interacting/CAST family member 1
Other Description ELKS/Rab6-interacting/CAST family member 1|RAB6 interacting protein 2
Swissprots Q9NXN5 D3DUP7 Q8IUD3 Q8IUD4 A2RU77 Q9UPS1 Q8IUD5 Q8IUD2 A7E295 Q8NAS1 Q9UIK7 Q6NVK2 D3DUP8
Accessions EAW88932 EAW88933 EAW88934 EAW88935 EAW88936 EAW88937 EAW88938 EAW88939 EAW88940 Q8IUD2 AB015617 BAA88763 AB029004 BAA83033 AB053468 BAC54107 AB053469 BAC54108 AB053470 BAC54109 AB053471 BAC54110 AK000148 BAA90975 AK056312 AK091577 AK092201 BAC03827 AK097177 AK294351 BAG57618 AK309992 BC005065 BC037377 BC068006 AAH68006 BC073885 BC132782 AAI32783 BC132784 AAI32785 BC144287 BC150248 AAI50249 BM984956 DR000847 XM_011520936 XP_011519238 XM_011520937 XP_011519239 XM_011520938 XP_011519240 XM_011520939 XP_011519241 XM_011520940 XP_011519242 XM_011520941 XP_011519243 XM_011520942 XP_011519244 XM_011520943 XP_011519245 XM_011520944 XP_011519246 XR_931508 XR_931509 XR_931510 NM_001301248 NP_001288177 NM_178039 NP_829883 NM_178040 NP_829884 NR_027946 NR_027948 NR_027949
Function Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. {ECO:0000269|PubMed:15218148}.
Subcellular Location Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=In neurons, localized closed to presynaptic membrane. Recruited on Golgi membranes by RAB6A in a GTP-dependent manner (By similarity). {ECO:0000250}.
Tissue Specificity Widely expressed. Isoform 2 and isoform 4 are abundantly expressed in brain. Isoform 1 and isoform 3 are predominantly expressed in testis and thyroid, and isoform 1 predominates in other tissues tested. {ECO:0000269|PubMed:12203787}.

ERC1 (P85) Antibody - 2884 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa (human), NIH/3T3 (mouse), NBT-II (rat) cell lines and from rat brain using ERC1 (P85) Antibody.

ERC1α (D1055) Antibody - 2885 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from ACHN, HeLa and SK-MEL-5 cells using ERC1α (D1055) Antibody.

ELKS (E-1) - sc-365715 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ELKS (E-1): sc-365715. Western blot analysis of ELKS expression in MIA PaCa-2 whole cell lysate.

ELKS (N-15) - sc-47876 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ELKS (N-15): sc-47876. Western blot analysis of ELKS expression in mouse testis tissue extract.

ELKS (H-48) - sc-135215 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ELKS (H-48): sc-135215. Western blot analysis of ELKS expression in non-transfected 293T: sc-117752 (A), mouse ELKS transfected 293T: sc-119999 (B) and NTERA-2 cl.D1 (C) whole cell lysates and mouse testis tissue extract (D).

ELKS (C-17) - sc-47875 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ELKS (C-17): sc-47875. Western blot analysis of ELKS expression in MIA PaCa-2 (A), NTERA-2 cl. D1 (B) and SW480 (C) whole cell lysates.

ELKS (N-20) - sc-47877 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ELKS (N-20): sc-47877. Western blot analysis of ELKS expression in MIA PaCa-2 whole cell lysate.

Anti-ERC1 antibody - ab21192 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-ERC1 antibody (ab21192) at 0.1 µg/ml + Tissue lysates prepared from human pancreas at 35 µg

Anti-ERC1 antibody - ab95889 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ERC1 antibody (ab95889) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µg

Anti-ERC1 antibody - ab95891 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ERC1 antibody (ab95891) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µg

Anti-ERC1 antibody - ab71567 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ERC1 antibody - ab172398 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-ERC1 antibody (ab172398) at 1 µg/mlLane 1 : ERC1 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-ERC1 antibody [ELKS-30] - ab50312 from Abcam

Prices $373.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone ELKS-30

Anti-ERC1 antibody [EPR13777] - ab180507 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13777
All lanes : Anti-ERC1 antibody [EPR13777] (ab180507) at 1/2000 dilutionLane 1 : HeLa cell lysateLane 2 : HEK293 cell lysateLane 3 : Jurkat cell lysateLane 4 : SW480 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-ELKS / ERC1 Antibody (N-Terminus) - LS-C144820 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ELKS / ERC1 Antibody (aa700-750) - LS-C289416 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ELKS / ERC1 Antibody (aa1000-1050) - LS-C289417 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ELKS / ERC1 Antibody (aa1066-1116) - LS-C289420 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ELKS / ERC1 Antibody (aa981-1030) - LS-C135535 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ERC1 antibody LS-C135535 Western blot of Fetal Muscle lysate.

Anti-ELKS / ERC1 Antibody (aa509-558) - LS-C201738 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Fetal Brain. ERC1 antibody dilution 1.0 ug/ml.

Anti-ELKS / ERC1 Antibody - LS-C307420 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

ELKS Antibody - NBP1-88177 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ELKS Antibody [NBP1-88177] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

ELKS Antibody - NBP1-88179 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ELKS Antibody [NBP1-88179] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)

ELKS Antibody - NBP1-88178 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ELKS Antibody [NBP1-88178] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)

ELKS Antibody - H00023085-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: ELKS Antibody [H00023085-B01] - analysis of RAB6IP2 expression in transfected 293T cell line by RAB6IP2 MaxPab polyclonal antibody (B01). Lane 1: RAB6IP2 transfected lysate (10.00 KDa). Lane 2: Non-transfected lysate.
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