ERC1

Gene Symbol	ERC1
Entrez Gene	23085
Alt Symbol	Cast2, ELKS, ERC-1, RAB6IP2
Species	Human
Gene Type	protein-coding
Description	ELKS/RAB6-interacting/CAST family member 1
Other Description	ELKS/Rab6-interacting/CAST family member 1|RAB6 interacting protein 2
Swissprots	Q9NXN5 D3DUP7 Q8IUD3 Q8IUD4 A2RU77 Q9UPS1 Q8IUD5 Q8IUD2 A7E295 Q8NAS1 Q9UIK7 Q6NVK2 D3DUP8
Accessions	EAW88932 EAW88933 EAW88934 EAW88935 EAW88936 EAW88937 EAW88938 EAW88939 EAW88940 Q8IUD2 AB015617 BAA88763 AB029004 BAA83033 AB053468 BAC54107 AB053469 BAC54108 AB053470 BAC54109 AB053471 BAC54110 AK000148 BAA90975 AK056312 AK091577 AK092201 BAC03827 AK097177 AK294351 BAG57618 AK309992 BC005065 BC037377 BC068006 AAH68006 BC073885 BC132782 AAI32783 BC132784 AAI32785 BC144287 BC150248 AAI50249 BM984956 DR000847 XM_011520936 XP_011519238 XM_011520937 XP_011519239 XM_011520938 XP_011519240 XM_011520939 XP_011519241 XM_011520940 XP_011519242 XM_011520941 XP_011519243 XM_011520942 XP_011519244 XM_011520943 XP_011519245 XM_011520944 XP_011519246 XR_931508 XR_931509 XR_931510 NM_001301248 NP_001288177 NM_178039 NP_829883 NM_178040 NP_829884 NR_027946 NR_027948 NR_027949
Function	Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. {ECO:0000269|PubMed:15218148}.
Subcellular Location	Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=In neurons, localized closed to presynaptic membrane. Recruited on Golgi membranes by RAB6A in a GTP-dependent manner (By similarity). {ECO:0000250}.
Tissue Specificity	Widely expressed. Isoform 2 and isoform 4 are abundantly expressed in brain. Isoform 1 and isoform 3 are predominantly expressed in testis and thyroid, and isoform 1 predominates in other tissues tested. {ECO:0000269|PubMed:12203787}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ERC1 full length protein - ab132224 from Abcam Category Protein Source Wheat germ Species Human

Human ERC1 peptide - ab45484 from Abcam Category Peptide Species Human

Human ERC1 protein fragment - ab161528 from Abcam Category Protein Source Wheat germ Species Human

ELKS / ERC1 Antibody Blocking Peptide - LS-E21768 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ELKS Protein - H00023085-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ELKS Protein - H00023085-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ELKS-Antibody-Center-Blocking-Peptide - BP9050c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ELKS/RAB6IP2 blocking peptide - GTX41192-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

ERC1 Blocking Peptide - 33R-4522 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ERC1 Peptide - AC21-0270-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ERC1 / ELKS - H00023085-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ERC1 / ELKS - H00023085-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ERC1 / ELKS - H00023085-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ERC1 / ELKS - H00023085-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ELKS Peptide - 45-529P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

ERC1 fusion protein - Ag17665 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

ERC1 fusion protein - Ag17536 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

ERC1 fusion protein - ag0966 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human ERC1, His-tagged - ERC1-12519H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human ELKS/Rab6-interacting/CAST family member 1(ERC1) ,partial - CSB-YP007767HU CSB-EP007767HU CSB-BP007767HU CSB-MP007767HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ERC1 / ELKS (transcript variant epsilon) - TP313864 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ELKS/RAB6IP2, Peptide - MBS425021 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

ELKS Recombinant Protein Antigen - NBP1-88179PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ELKS Protein - NBP1-88178PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ELKS Recombinant Protein Antigen - NBP1-88177PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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