ERC1

Gene Symbol ERC1
Entrez Gene 23085
Alt Symbol Cast2, ELKS, ERC-1, RAB6IP2
Species Human
Gene Type protein-coding
Description ELKS/RAB6-interacting/CAST family member 1
Other Description ELKS/Rab6-interacting/CAST family member 1|RAB6 interacting protein 2
Swissprots Q9NXN5 D3DUP7 Q8IUD3 Q8IUD4 A2RU77 Q9UPS1 Q8IUD5 Q8IUD2 A7E295 Q8NAS1 Q9UIK7 Q6NVK2 D3DUP8
Accessions EAW88932 EAW88933 EAW88934 EAW88935 EAW88936 EAW88937 EAW88938 EAW88939 EAW88940 Q8IUD2 AB015617 BAA88763 AB029004 BAA83033 AB053468 BAC54107 AB053469 BAC54108 AB053470 BAC54109 AB053471 BAC54110 AK000148 BAA90975 AK056312 AK091577 AK092201 BAC03827 AK097177 AK294351 BAG57618 AK309992 BC005065 BC037377 BC068006 AAH68006 BC073885 BC132782 AAI32783 BC132784 AAI32785 BC144287 BC150248 AAI50249 BM984956 DR000847 XM_011520936 XP_011519238 XM_011520937 XP_011519239 XM_011520938 XP_011519240 XM_011520939 XP_011519241 XM_011520940 XP_011519242 XM_011520941 XP_011519243 XM_011520942 XP_011519244 XM_011520943 XP_011519245 XM_011520944 XP_011519246 XR_931508 XR_931509 XR_931510 NM_001301248 NP_001288177 NM_178039 NP_829883 NM_178040 NP_829884 NR_027946 NR_027948 NR_027949
Function Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. {ECO:0000269|PubMed:15218148}.
Subcellular Location Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=In neurons, localized closed to presynaptic membrane. Recruited on Golgi membranes by RAB6A in a GTP-dependent manner (By similarity). {ECO:0000250}.
Tissue Specificity Widely expressed. Isoform 2 and isoform 4 are abundantly expressed in brain. Isoform 1 and isoform 3 are predominantly expressed in testis and thyroid, and isoform 1 predominates in other tissues tested. {ECO:0000269|PubMed:12203787}.

ELKS CRISPR/Cas9 KO Plasmid (h) - sc-404216 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELKS HDR Plasmid (h) - sc-404216-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELKS Double Nickase Plasmid (h) - sc-404216-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELKS Double Nickase Plasmid (h2) - sc-404216-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELKS CRISPR Activation Plasmid (h) - sc-404216-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELKS CRISPR Activation Plasmid (h2) - sc-404216-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELKS Lentiviral Activation Particles (h) - sc-404216-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELKS Lentiviral Activation Particles (h2) - sc-404216-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELKS siRNA (h) - sc-60572 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ELKS shRNA Plasmid (h) - sc-60572-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ELKS shRNA (h) Lentiviral Particles - sc-60572-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU124071 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7947 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7947 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ERC1 siRNA (Human) - CRH7986 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERC1 - MBS8207422 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ERC1 (NM_178040.2) - SHH286853 from Creative biogene

Category siRNA
Species Reactivities Human

Human ERC1 siRNA - orb268488 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERC1 shRNA Plasmid (Human) - CHH7986 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
Search more