HORMAD1

Gene Symbol	HORMAD1
Entrez Gene	84072
Alt Symbol	CT46, NOHMA
Species	Human
Gene Type	protein-coding
Description	HORMA domain containing 1
Other Description	HORMA domain-containing protein 1|cancer/testis antigen 46|newborn ovary HORMA protein
Swissprots	Q5T5I3 Q86X24 Q4G114 Q6FIC1 Q5T5I5 Q5T5I4 B3KUK1 A6NMK2 Q9H0K8
Accessions	CBH30631 EAW53520 EAW53521 EAW53522 EAW53523 EAW53524 EAW53525 Q86X24 AA991355 AK097390 BAG53463 AK098633 AL136755 CAB66689 AM392561 CAL37439 AM392979 CAL37857 AY626344 AAT45740 BC033014 AAH33014 BC047406 AAH47406 BU570274 CR533505 CAG38536 XM_006711569 XP_006711632 XM_006711570 XP_006711633 XM_006711571 XP_006711634 XM_011510053 XP_011508355 XM_011510054 XP_011508356 XM_011510055 XP_011508357 XM_011510056 XP_011508358 NM_001199829 NP_001186758 NM_032132 NP_115508
Function	Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser-377 is restricted to unsynapsed chromosomal regions (By similarity). {ECO:0000250}.
Tissue Specificity	Testis-specific. Over-expressed in carcinomas. {ECO:0000269|PubMed:15999985}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HORMAD1 full length protein - ab164488 from Abcam Category Protein Source Wheat germ Species Human

HORMAD1 Antibody Blocking Peptide - LS-E6007 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HORMAD1 Recombinant Protein - H00084072-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

HORMAD1-Antibody-Center-Blocking-Peptide - BP18581c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HORMAD1 peptide - orb218674 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg

HORMAD1 Blocking Peptide - abx064005 from Abbexa Category Peptide Species Human, Monkey

HORMAD1 / NOHMA - H00084072-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

HORMAD1 / NOHMA - H00084072-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HORMAD1 fusion protein - ag4914 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

HORMAD1 Blocking Peptide - CBP2811 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Monkey

Recombinant Human HORMA domain-containing protein 1(HORMAD1) - CSB-YP803140HU CSB-EP803140HU CSB-BP803140HU CSB-MP803140HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HORMAD1 / NOHMA (full length, N-term HIS tag, transcript variant 1) - TP760876 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

HORMAD1 Recombinant Protein Antigen - NBP1-85401PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HORMAD1 Peptide, Human - M34GP07180H from Creative Peptides Category Peptide Source Synthetic. Species Human

HORMAD1 Recombinant Protein Antigen - NBP2-54973PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HORMA domain-containing protein 1 (HORMAD1), Recombinant Protein - MBS1474521 from MyBioSource Category Protein Prices $1,165.00, $1,165.00, $1,395.00, $1,395.00, $1,865.00, $1,865.00, $2,330.00, $2,330.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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