DHRS9

Gene Symbol	DHRS9
Entrez Gene	10170
Alt Symbol	3-alpha-HSD, 3ALPHA-HSD, RDH-E2, RDH-TBE, RDH15, RDHL, RDHTBE, RETSDR8, SDR9C4
Species	Human
Gene Type	protein-coding
Description	dehydrogenase/reductase (SDR family) member 9
Other Description	3-alpha hydroxysteroid dehydrogenase|NADP-dependent retinol dehydrogenase/reductase|dehydrogenase/reductase SDR family member 9|retinol dehydrogenase 15|retinol dehydrogenase homolog|short chain dehydrogenase/reductase family 9C member 4|short chain dehydrogenase/reductase family 9C, member 4|short-chain dehydrogenase/reductase retSDR8|tracheobronchial epithelial cell-specific retinol dehydrogenase
Swissprots	D3DPC1 Q9NRB0 Q9NRA9 Q5RKX1 B7Z416 Q9BPW9
Accessions	AAX88964 AAY24306 EAX11282 EAX11283 EAX11284 Q9BPW9 AF067174 AAD32458 AF240697 AAF82747 AF240698 AAF82748 AF295380 AAL37037 AF343729 AAK37528 AF529286 AAN04008 AF529287 AAN04009 AF529288 AAN04010 AK296625 BAH12402 AK313220 BAG36032 AY017349 AAG49422 AY359046 AAQ89405 BC040380 BC051797 BC058883 AAH58883 CA307349 DB010228 GQ129414 ACT64548 GQ129415 ACT64549 HQ448109 ADQ32590 XM_011510475 XP_011508777 XM_011510476 XP_011508778 NM_001142270 NP_001135742 NM_001142271 NP_001135743 NM_001289763 NP_001276692 NM_199204 NP_954674 NM_005771
Function	3-alpha-hydroxysteroid dehydrogenase that converts 3- alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. May play a role in the biosynthesis of retinoic acid from retinaldehyde, but seems to have low activity with retinoids. Can utilize both NADH and NADPH. {ECO:0000269|PubMed:11294878, ECO:0000269|PubMed:11304534, ECO:0000269|PubMed:12618084}.
Subcellular Location	Microsome membrane {ECO:0000269|PubMed:11294878, ECO:0000269|PubMed:11304534, ECO:0000269|PubMed:12618084}. Endoplasmic reticulum membrane {ECO:0000305}. Note=Associated with microsomal membranes.
Tissue Specificity	Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node. {ECO:0000269|PubMed:11294878, ECO:0000269|PubMed:11304534, ECO:0000269|PubMed:12618084}.
Top Pathways	Retinol metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DHRS9 full length protein - ab123162 from Abcam Category Protein Source E. coli Species Human

DHRS9 Antibody Blocking Peptide - LS-E19313 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DHRS9 Recombinant Protein - H00010170-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human DHRS9 Protein - NBP1-78842 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E. coli Species Human

DHRS9-Antibody-Center-Blocking-Peptide - BP10479c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human DHRS9 (His Tag) protein - orb179534 from Biorbyt Category Protein Prices $417.00, $859.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Human DHRS9 protein - orb168232 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

DHRS9 Blocking Peptide - 33R-2120 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DHRS9 protein (His tag) - 80R-2085 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

DHRS9 (18-319, His-tag) - AR50168PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

DHRS9 (18-319, His-tag) - AR50168PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

DHRS9 - H00010170-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

DHRS9 fusion protein - ag6116 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

DHRS9 fusion protein - ag6422 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

DHRS9 Human - ENPS-223 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Dehydrogenase/Reductase Member 9 Enzyme - BP002766-ENZ-216 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

Recombinant Human Dehydrogenase/Reductase (SDR Family) Member 9, His-tagged - DHRS9-1561H from Creative Biomart Category Protein

Recombinant Human DHRS9, His-tagged - DHRS9-270H from Creative Biomart Category Protein Source E. coli Species Human

DHRS9 18-319aa - CMB-1176 from Reagent Proteins Category Protein Prices $539.00, $1,099.00 Sizes 50.00 µg, 250.00 µg Source E.coli Species Human

Human DHRS9 Protein (His Tag) - 15253-H07E-20 from Sino Biological Category Protein Source E. coli Species Human

Recombinant Human Dehydrogenase/reductase SDR family member 9(DHRS9) - CSB-YP859827HU CSB-EP859827HU CSB-BP859827HU CSB-MP859827HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DHRS9 (transcript variant 2) - TP320853 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

DHRS9 (transcript variant 3) - TP326895 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

DHRS9 (transcript variant 4) - TP326904 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

DHRS9 Protein - NBP1-89379PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

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