DHRS9

Gene Symbol DHRS9
Entrez Gene 10170
Alt Symbol 3-alpha-HSD, 3ALPHA-HSD, RDH-E2, RDH-TBE, RDH15, RDHL, RDHTBE, RETSDR8, SDR9C4
Species Human
Gene Type protein-coding
Description dehydrogenase/reductase (SDR family) member 9
Other Description 3-alpha hydroxysteroid dehydrogenase|NADP-dependent retinol dehydrogenase/reductase|dehydrogenase/reductase SDR family member 9|retinol dehydrogenase 15|retinol dehydrogenase homolog|short chain dehydrogenase/reductase family 9C member 4|short chain dehydrogenase/reductase family 9C, member 4|short-chain dehydrogenase/reductase retSDR8|tracheobronchial epithelial cell-specific retinol dehydrogenase
Swissprots D3DPC1 Q9NRB0 Q9NRA9 Q5RKX1 B7Z416 Q9BPW9
Accessions AAX88964 AAY24306 EAX11282 EAX11283 EAX11284 Q9BPW9 AF067174 AAD32458 AF240697 AAF82747 AF240698 AAF82748 AF295380 AAL37037 AF343729 AAK37528 AF529286 AAN04008 AF529287 AAN04009 AF529288 AAN04010 AK296625 BAH12402 AK313220 BAG36032 AY017349 AAG49422 AY359046 AAQ89405 BC040380 BC051797 BC058883 AAH58883 CA307349 DB010228 GQ129414 ACT64548 GQ129415 ACT64549 HQ448109 ADQ32590 XM_011510475 XP_011508777 XM_011510476 XP_011508778 NM_001142270 NP_001135742 NM_001142271 NP_001135743 NM_001289763 NP_001276692 NM_199204 NP_954674 NM_005771
Function 3-alpha-hydroxysteroid dehydrogenase that converts 3- alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. May play a role in the biosynthesis of retinoic acid from retinaldehyde, but seems to have low activity with retinoids. Can utilize both NADH and NADPH. {ECO:0000269|PubMed:11294878, ECO:0000269|PubMed:11304534, ECO:0000269|PubMed:12618084}.
Subcellular Location Microsome membrane {ECO:0000269|PubMed:11294878, ECO:0000269|PubMed:11304534, ECO:0000269|PubMed:12618084}. Endoplasmic reticulum membrane {ECO:0000305}. Note=Associated with microsomal membranes.
Tissue Specificity Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node. {ECO:0000269|PubMed:11294878, ECO:0000269|PubMed:11304534, ECO:0000269|PubMed:12618084}.
Top Pathways Retinol metabolism

DHRS9 (G-15) - sc-103467 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DHRS9 (G-15): sc-103467. Western blot analysis of DHRS9 expression in non-transfected: sc-117752 (A) and human DHRS9 transfected: sc-371280 (B) 293T whole cell lysates.

Anti-DHRS9 antibody - ab98155 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-DHRS9 antibody (ab98155) at 1 µg/ml + THP-1 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-DHRS9 antibody - ab89698 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DHRS9 antibody - ab126074 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DHRS9 antibody (ab126074) at 1/1000 dilutionLane 1 : NT2D1 whole cell lysateLane 2 : SK N SH whole cell lysateLysates/proteins at 30 µg per lane.

Anti-DHRS9 antibody - ab70145 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-DHRS9 antibody (ab70145) at 1/500 dilutionLane 1 : DHRS9 transfected 293T cell lysateLane 2 : non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-DHRS9 Antibody - LS-C145077 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DHRS9 Antibody - LS-C307248 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DHRS9 Antibody - LS-C307246 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-DHRS9 Antibody (aa215-264) - LS-C107734 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DHRS9 antibody LS-C107734 Western blot of THP-1 cell lysate.

Anti-DHRS9 Antibody - LS-C310127 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DHRS9 Antibody - LS-C310126 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DHRS9 Antibody (HRP) - LS-C317247 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DHRS9 Antibody (Biotin) - LS-C317248 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DHRS9 Antibody (FITC) - LS-C317250 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DHRS9 Antibody - LS-C317245 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human kidney using DHRS9 antibody at dilution of 1:100.

Anti-DHRS9 Antibody - LS-C334641 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using DHRS9 antibody.

DHRS9 Antibody - NBP1-89379 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DHRS9 Antibody [NBP1-89379] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

DHRS9 Antibody - NBP1-58043 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DHRS9 Antibody [NBP1-58043] - THP-1 cell lysate, concentration 0.2-1 ug/ml.

DHRS9 Antibody - H00010170-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: DHRS9 Antibody [H00010170-B01P] - Analysis of DHRS9 expression in A-431.

DHRS9 Antibody - NBP1-89378 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DHRS9 Antibody [NBP1-89378] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

DHRS9 Antibody - NBP1-30022 from Novus Biologicals

Prices $329.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

DHRS9 Antibody - H00010170-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DHRS9 Antibody [H00010170-D01P] - Analysis of DHRS9 expression in A-431.

DHRS9 Antibody - NBP2-16160 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DHRS9 Antibody [NBP2-16160] - Sample (30 ug of whole cell lysate) A: NT2D1 B: SK-N-SH 10% SDS PAGE gel, diluted at 1:1000.

DHRS9 Antibody (3E3) - H00010170-M06 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E3
Western Blot: DHRS9 Antibody (3E3) [H00010170-M06] - Analysis of DHRS9 expression in transfected 293T cell line by DHRS9 monoclonal antibody (M06), clone 3E3. Lane 1: DHRS9 transfected lysatE (35.2 KDa). Lane 2: Non-transfected lysate.

DHRS9 Antibody (3C6) - H00010170-M05 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3C6
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