TAAR1

Gene Symbol TAAR1
Entrez Gene 134864
Alt Symbol TA1, TAR1, TRAR1
Species Human
Gene Type protein-coding
Description trace amine associated receptor 1
Other Description taR-1|trace amine receptor 1|trace amine-associated receptor 1
Swissprots Q5VUQ1 Q96RJ0 Q2M1W5 Q3MIH8
Accessions AAG17112 AAK71236 EAW48021 Q96RJ0 AY180374 AAO22154 BC101825 AAI01826 BC112194 AAI12195 NM_138327 NP_612200
Function Receptor for trace amines, including beta- phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase. {ECO:0000269|PubMed:15718104}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Detected in low levels in discrete regions within the central nervous system and in several peripheral tissues. Moderately expressed in stomach. Low levels in amygdala, kidney, and lung, and small intestine. Trace amounts in cerebellum, dorsal root ganglia, hippocampus, hypothalamus, liver, medulla, pancreas, pituitary, pontine reticular formation, prostate, skeletal muscle and spleen.
Top Pathways Neuroactive ligand-receptor interaction

TAAR1 (E-12) - sc-50184 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TaR (H-35) - sc-134818 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

TaR (S-13) - sc-50182 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TA1 antibody - ab65633 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab65633 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab65633, 1/1000 dilution) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-mouse IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-TA1 antibody - ab72194 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TA1 antibody (ab72194) at 2 µg/mlLane 1 : Human brain lysate Lane 2 : Rat brain lysate

Anti-TA1 antibody - N-terminal - ab189016 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded human brain amygdala tissue labeling TA1 using ab189016 at 1.3 µg/ml.

Anti-TAAR1 / TA1 Antibody (aa200-230) - LS-C47337 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot ofhumanTAAR1 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse brain lysate and 4) rat brain lysate using antibody at 2 ug/ml.

Anti-TAAR1 / TA1 Antibody (Extracellular Domain) IHC-plus™ - LS-A2042 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TAAR1 antibody LS-A2042 IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TAAR1 / TA1 Antibody (N-Terminus) IHC-plus™ - LS-A2043 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TAAR1 antibody LS-A2043 IHC of human brain, amygdala. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TAAR1 / TA1 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A2040 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TAAR1 antibody LS-A2040 IHC of human brain, amygdala. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TAAR1 / TA1 Antibody (aa225-250) IHC-plus™ - LS-B1773 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TAAR1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1773 concentration 10 ug/ml.

Anti-TAAR1 / TA1 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A2041 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TAAR1 antibody LS-A2041 IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Trace Amine Receptor 1 Antibody - NBP2-24714 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Trace Amine Receptor 1 Antibody [NBP2-24714] - Analysis of human TAAR1 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse brain lysate and 4) rat brain lysate using NBP2-24714 at 2 ug/ml.

Trace Amine Receptor 1 Antibody - NBP2-24720 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Trace Amine Receptor 1 Antibody [NBP2-24720] - Analysis of human TAAR1 in human brain and rat brain lysate using NBP2-24720 at 2 ug/ml.

Trace Amine Receptor 1 Antibody - NLS2042 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Trace Amine Receptor 1 Antibody [NLS2042] - Analysis of anti-TAAR1 antibody with human brain, neurons at 6 ug/ml.

Trace Amine Receptor 1 Antibody - NBP2-38762 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Trace Amine Receptor 1 Antibody [NBP2-38762] - Staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells.

Trace Amine Receptor 1 Antibody - NB110-55292 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Trace Amine Receptor 1 Antibody [NB110-55292] - Analysis of anti-TAAR1 antibody with human brain, amygdala at 28 ug/ml.

Anti-TAAR1/TA1 antibody produced in rabbit - SAB2900032 from Sigma-Aldrich

Prices $464.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TAAR1/TA1: <B>Cat. No.SAB2900032</B>: Brain, Amygdala: Formalin-Fixed Paraffin-Embedded (FFPE).

Anti-TAAR1 antibody produced in rabbit - SAB2900498 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TAAR1 (N-Terminus), antibody produced in rabbit: <B>Cat. No. SAB2900498</B>: Anti-TAAR1 antibody IHC staining of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TAAR1 antibody - orb85547 from Biorbyt

Prices $536.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of paraffin embedded human brain tissue using TAAR1 antibody (primary antibody at 1:200)

TAAR1 Antibody (OALA00385) - OALA00385 from Aviva Systems Biology

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

TAAR1 Antibody (OALA00386) - OALA00386 from Aviva Systems Biology

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

TAAR1 Antibody (OALA00387) - OALA00387 from Aviva Systems Biology

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

TAAR1 Antibody (OALA00388) - OALA00388 from Aviva Systems Biology

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

TAAR1 Antibody (OALA02124) - OALA02124 from Aviva Systems Biology

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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