TAAR1

Gene Symbol	TAAR1
Entrez Gene	134864
Alt Symbol	TA1, TAR1, TRAR1
Species	Human
Gene Type	protein-coding
Description	trace amine associated receptor 1
Other Description	taR-1|trace amine receptor 1|trace amine-associated receptor 1
Swissprots	Q5VUQ1 Q96RJ0 Q2M1W5 Q3MIH8
Accessions	AAG17112 AAK71236 EAW48021 Q96RJ0 AY180374 AAO22154 BC101825 AAI01826 BC112194 AAI12195 NM_138327 NP_612200
Function	Receptor for trace amines, including beta- phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase. {ECO:0000269|PubMed:15718104}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Detected in low levels in discrete regions within the central nervous system and in several peripheral tissues. Moderately expressed in stomach. Low levels in amygdala, kidney, and lung, and small intestine. Trace amounts in cerebellum, dorsal root ganglia, hippocampus, hypothalamus, liver, medulla, pancreas, pituitary, pontine reticular formation, prostate, skeletal muscle and spleen.
Top Pathways	Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TA1 full length protein - ab165386 from Abcam Category Protein Source Wheat germ Species Human

TAAR1 / TA1 Antibody Blocking Peptide - LS-E28476 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TAAR1 / TA1 Antibody Blocking Peptide - LS-E28477 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TAAR1 / TA1 Antibody Blocking Peptide - LS-E28479 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TAAR1 / TA1 Antibody Blocking Peptide - LS-E28478 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human Trace Amine Receptor 1 Protein - H00134864-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

TAAR1 - H00134864-G01 from Acris Antibodies Category Protein Prices $440.00 Sizes 2 µg Species Human

TAAR1 - H00134864-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

TAAR1 fusion protein - ag13018 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Trace Amine Receptor 1 Protein - H00134864-G01 from Novus Biologicals Category Protein Prices $415.00 Sizes 2 µg Source Wheat Germ Species Human

Trace Amine Receptor 1 Protein - NBP2-38762PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

TAAR1 Peptide, Human - M34GP15517H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein TAR1 (TAR1-A), Recombinant Protein - MBS1361550 from MyBioSource Category Protein Prices $845.00, $845.00, $1,065.00, $1,065.00, $1,215.00, $1,215.00, $1,670.00, $1,670.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Kluyveromyces

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