Gene Symbol |
IL17RA
|
Entrez Gene |
23765
|
Alt Symbol |
CANDF5, CD217, CDw217, IL-17RA, IL17R, hIL-17R
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
interleukin 17 receptor A
|
Other Description |
IL-17 receptor A|interleukin-17 receptor A
|
Swissprots |
O43844 Q20WK1 Q96F46
|
Accessions |
CAL44890 CAV28582 CCB07364 EAW57738 EAW57739 EAW57740 EAW57741 Q96F46 AF021799 AK056836 AK093772 BC011624 AAH11624 BC012071 BE242733 BU585070 BX334547 BX368715 BX410574 CB044543 CT841520 CAJ86450 DQ891962 ABM82888 DQ895152 ABM86078 JF305973 ADY18334 U58917 AAB99730 NM_001289905 NP_001276834 NM_014339 NP_055154
|
Function |
Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling. {ECO:0000269|PubMed:19838198, ECO:0000269|PubMed:21993848}.
|
Subcellular Location |
Isoform 1: Membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}.
|
Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:21993848}.
|
Top Pathways |
Cytokine-cytokine receptor interaction
|