Gene Symbol | IL17RA |
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Entrez Gene | 23765 |
Alt Symbol | CANDF5, CD217, CDw217, IL-17RA, IL17R, hIL-17R |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 17 receptor A |
Other Description | IL-17 receptor A|interleukin-17 receptor A |
Swissprots | O43844 Q20WK1 Q96F46 |
Accessions | CAL44890 CAV28582 CCB07364 EAW57738 EAW57739 EAW57740 EAW57741 Q96F46 AF021799 AK056836 AK093772 BC011624 AAH11624 BC012071 BE242733 BU585070 BX334547 BX368715 BX410574 CB044543 CT841520 CAJ86450 DQ891962 ABM82888 DQ895152 ABM86078 JF305973 ADY18334 U58917 AAB99730 NM_001289905 NP_001276834 NM_014339 NP_055154 |
Function | Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling. {ECO:0000269|PubMed:19838198, ECO:0000269|PubMed:21993848}. |
Subcellular Location | Isoform 1: Membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:21993848}. |
Top Pathways | Cytokine-cytokine receptor interaction |
Active human IL17A Receptor protein fragment - ab167753 from Abcam
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Human IL17A Receptor protein fragment - ab161762 from Abcam
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Human IL17A Receptor protein fragment - ab194021 from Abcam
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IL17RA Antibody Blocking Peptide - LS-E6093 from LifeSpan Bioscience
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IL17RA Antibody Blocking Peptide - LS-E31458 from LifeSpan Bioscience
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IL17RA Antibody Blocking Peptide - LS-E26383 from LifeSpan Bioscience
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Recombinant Human IL-17 RA/IL-17 R Protein - H00023765-Q01 from Novus Biologicals
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Recombinant Human IL-17 RA/IL-17 R Protein - H00023765-G01 from Novus Biologicals
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Recombinant Human IL-17 RA/IL-17 R Fc Chimera, CF - 177-IR-100 from R&D Systems
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Cynomolgus IL17RA protein - orb139124 from Biorbyt
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Canine CD217 protein - orb139120 from Biorbyt
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Marmoset CD217 protein - orb139121 from Biorbyt
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Human IL17RA Protein - abx067463 from Abbexa
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Human IL17RA Protein - abx067464 from Abbexa
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CD217 / IL17RA - H00023765-Q01-10 from Acris Antibodies
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CD217 / IL17RA - H00023765-Q01-25 from Acris Antibodies
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CD217 / IL17RA Control Peptide - AP10109CP-N from Acris Antibodies
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Interleukin 17 Receptor A (IL17RA), Human - 20-7883 from ARP American Research Products
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Interleukin 17 Receptor A (IL17RA), Human - 20-7884 from ARP American Research Products
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IL-17RA Peptide - 7419P from ProSci
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IL17 R Recombinant Protein - 96-453 from ProSci
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IL17 RA Recombinant Protein - 96-456 from ProSci
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IL17RA fusion protein - ag2955 from Proteintech Group
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IL17RA fusion protein - ag2688 from Proteintech Group
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Recombinant Human IL17RA, His tagged - IL17RA-2197H from Creative Biomart
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