NCBP2

Gene Symbol	NCBP2
Entrez Gene	22916
Alt Symbol	CBC2, CBP20, NIP1, PIG55
Species	Human
Gene Type	protein-coding
Description	nuclear cap binding protein subunit 2, 20kDa
Other Description	20 kDa nuclear cap-binding protein|NCBP 20 kDa subunit|NCBP interacting protein 1|NCBP-interacting protein 1|cell proliferation-inducing gene 55 protein|nuclear cap binding protein subunit 2, 20kD|nuclear cap-binding protein subunit 2
Swissprots	B2RE91 B4DMK7 Q14924 P52298 Q2TS50 E9PAR5
Accessions	EAW53620 EAW53621 EAW53622 EAW53623 EAW53624 P52298 AK093216 BAG52672 AK296144 BAG58884 AK297506 BAG59919 AK308192 AK315903 BAH14274 AK316601 BAG38188 AL110262 AW440347 AY644767 AAV85455 BC001255 AAH01255 BP248419 BT006842 AAP35488 BX537372 CAD97614 BX647994 CN421262 D59253 BAA09599 DC375323 DQ890703 ABM81629 DQ893887 ABM84813 X84157 CAA58962 XM_005269313 XP_005269370 XM_011512556 XP_011510858 XM_011512557 XP_011510859 XM_011512558 XP_011510860 NM_001042540 NP_001036005 NM_001308036 NP_001294965 NM_007362 NP_031388
Function	Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC com
Subcellular Location	Nucleus {ECO:0000269|PubMed:8601613}. Cytoplasm {ECO:0000269|PubMed:8601613}.
Top Pathways	Spliceosome, RNA transport, mRNA surveillance pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NCBP2 full length protein - ab101195 from Abcam Category Protein Source E. coli Species Human

CBP20 Partial Recombinant Protein - H00022916-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CBP20 Recombinant Protein - H00022916-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human CBP20 Protein - NBP1-49435 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E.coli Species Human

NCBP2 Protein (OPPA02617) - OPPA02617 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human NCBP2 protein - orb168903 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

NCBP2 protein (His tag) - 80R-1509 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

NCBP2 (1-156, His-tag) - AR09685PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

NCBP2 (1-156, His-tag) - AR09685PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

NCBP2 - H00022916-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NCBP2 - H00022916-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NCBP2 - H00022916-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NCBP2 - H00022916-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NCBP2, 1-156aa, Human, His tag, E.coli - 01-NCBP-2 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

CBP20 fusion protein - Ag2550 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

NCBP2 Human - PRPS-272 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human NCBP2 Protein - BP003022-PRO-265 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

NCBP2, 1-156aa, Recombinant Protein - GWB-P1291D from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

NCBP2 Human Protein - GWB-BSP546 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human CBP20, GST-tagged - CBP20-10761H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human NCBP2, His-tagged - NCBP2-2847H from Creative Biomart Category Protein Source E.coli.

Recombinant Human NCBP2, His-tagged - NCBP2-29865TH from Creative Biomart Category Protein Source E. coli Species Human

NCBP2 - NKX-328 from Reagent Proteins Category Protein Prices $364.00, $2,898.00 Sizes 20.00 µg, 1 mg Source E.coli

NCBP2 1-156aa - CMB-580 from Reagent Proteins Category Protein Prices $469.00, $889.00 Sizes 100.00 µg, 500 µg Source E.coli Species Human

CBP20 (R21) Peptide - BS2012P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Search more