| Gene Symbol |
SIGLEC12
|
| Entrez Gene |
89858
|
| Alt Symbol |
S2V, SIGLECL1, SLG, Siglec-XII
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sialic acid binding Ig-like lectin 12 (gene/pseudogene)
|
| Other Description |
SIGLEC-like 1|sialic acid-binding Ig-like lectin 12|sialic acid-binding Ig-like lectin-like 1
|
| Swissprots |
Q8IYH7 Q96PQ1
|
| Accessions |
AAK51233 AAK51234 EAW72022 EAW72023 Q96PQ1 AF282256 AAK71521 AI132995 AK095919 BAG53167 AK225931 AY358140 AAQ88507 BC035809 AAH35809 DA562082 XM_011527441 XP_011525743 XM_011527442 XP_011525744 NM_033329 NP_201586 NM_053003 NP_443729
|
| Function |
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Isoform Short is highly expressed in spleen, small intestine and adrenal gland; it is lower expressed in thyroid, placenta, brain, stomach, bone marrow, spinal chord and breast. Isoform Long is highly expressed in spleen, small intestine and bone marrow; it is lower expressed in thyroid, placenta, thymus, trachea, stomach, lung, adrenal gland, fetal brain and testis.
|