Gene Symbol | SIGLEC12 |
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Entrez Gene | 89858 |
Alt Symbol | S2V, SIGLECL1, SLG, Siglec-XII |
Species | Human |
Gene Type | protein-coding |
Description | sialic acid binding Ig-like lectin 12 (gene/pseudogene) |
Other Description | SIGLEC-like 1|sialic acid-binding Ig-like lectin 12|sialic acid-binding Ig-like lectin-like 1 |
Swissprots | Q8IYH7 Q96PQ1 |
Accessions | AAK51233 AAK51234 EAW72022 EAW72023 Q96PQ1 AF282256 AAK71521 AI132995 AK095919 BAG53167 AK225931 AY358140 AAQ88507 BC035809 AAH35809 DA562082 XM_011527441 XP_011525743 XM_011527442 XP_011525744 NM_033329 NP_201586 NM_053003 NP_443729 |
Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Isoform Short is highly expressed in spleen, small intestine and adrenal gland; it is lower expressed in thyroid, placenta, brain, stomach, bone marrow, spinal chord and breast. Isoform Long is highly expressed in spleen, small intestine and bone marrow; it is lower expressed in thyroid, placenta, thymus, trachea, stomach, lung, adrenal gland, fetal brain and testis. |
Siglec-12 CRISPR/Cas9 KO Plasmid (h) - sc-413805 from Santa Cruz Biotechnology
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Siglec-12 HDR Plasmid (h) - sc-413805-HDR from Santa Cruz Biotechnology
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Siglec-12 Double Nickase Plasmid (h) - sc-413805-NIC from Santa Cruz Biotechnology
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Siglec-12 Double Nickase Plasmid (h2) - sc-413805-NIC-2 from Santa Cruz Biotechnology
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Siglec-12 CRISPR Activation Plasmid (h) - sc-413805-ACT from Santa Cruz Biotechnology
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Siglec-12 CRISPR Activation Plasmid (h2) - sc-413805-ACT-2 from Santa Cruz Biotechnology
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Siglec-12 Lentiviral Activation Particles (h) - sc-413805-LAC from Santa Cruz Biotechnology
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Siglec-12 Lentiviral Activation Particles (h2) - sc-413805-LAC-2 from Santa Cruz Biotechnology
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Siglec-12 siRNA (h) - sc-61552 from Santa Cruz Biotechnology
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Siglec-12 shRNA Plasmid (h) - sc-61552-SH from Santa Cruz Biotechnology
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Siglec-12 shRNA (h) Lentiviral Particles - sc-61552-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU037261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19329 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19329 from Sigma-Aldrich
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SIGLEC12 siRNA (Human) - CRJ3871 from Cohesion Biosciences
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SIGLEC12 - MBS8227682 from MyBioSource
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shRNA set against Human SIGLEC12 (NM_033329.1) - SHH407444 from Creative biogene
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shRNA set against Human SIGLEC12(NM_053003.2) - SHR225407 from Creative biogene
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Human SIGLEC12 siRNA - orb274372 from Biorbyt
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SIGLEC12 shRNA Plasmid (Human) - CHJ3871 from Cohesion Biosciences
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SIGLEC12 miRNA 3'UTR clone - MiUTR1H-09393 from Creative biogene
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SIGLEC12 miRNA 3'UTR clone - MiUTR1H-09394 from Creative biogene
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