AP3S2

Gene Symbol	AP3S2
Entrez Gene	10239
Alt Symbol	AP3S3, sigma3b
Species	Human
Gene Type	protein-coding
Description	adaptor-related protein complex 3, sigma 2 subunit
Other Description	AP-3 complex subunit sigma-2|AP-3 complex subunit sigma-3B|adapter-related protein complex 3 subunit sigma-2|adaptor complex sigma3B|adaptor-related protein complex 3 subunit sigma-2|clathrin-associated/assembly/adaptor protein, small 4, 22-kD|sigma-3B-adaptin|sigma-adaptin 3b
Swissprots	Q53H83 B2R677 B4DGQ3 P59780
Accessions	EAX02071 EAX02072 EAX02073 EAX02074 EAX02075 P59780 AK222698 BAD96418 AK294712 BAG57864 AK312467 BAG35374 AL109702 AL110108 AW402906 BC002785 AAH02785 BC007773 AAH07773 BC010020 AAH10020 BC010615 BX098014 DA268327 DA337392 DA464242 DA752479 DA777624 DB322370 DC340463 DC410373 DQ892982 ABM83908 DQ896230 ABM87229 DR158459 X99459 CAA67824 NM_005829 NP_005820 NR_023361 NR_037582
Function	Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Subcellular Location	Golgi apparatus. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. {ECO:0000250}.
Tissue Specificity	Present in all adult tissues examined. {ECO:0000269|PubMed:9118953}.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AP3S2 293T Cell Transient Overexpression Lysate(Denatured) - H00010239-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

AP3S2 293 Cell Lysate - 407967 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

AP3S2 Overexpression Lysate (Denatured) - H00010239-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

AP3S2 Overexpression Lysate (Native) - NBL1-07587 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

AP3S2 Over-expression Lysate Product - GWB-B1FA3C from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human AP3S2 Knockdown Stable Cell Line - CSC-DC000728 from Creative biogene Category Cell Line Species Human

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