AP3S2

Gene Symbol	AP3S2
Entrez Gene	10239
Alt Symbol	AP3S3, sigma3b
Species	Human
Gene Type	protein-coding
Description	adaptor-related protein complex 3, sigma 2 subunit
Other Description	AP-3 complex subunit sigma-2|AP-3 complex subunit sigma-3B|adapter-related protein complex 3 subunit sigma-2|adaptor complex sigma3B|adaptor-related protein complex 3 subunit sigma-2|clathrin-associated/assembly/adaptor protein, small 4, 22-kD|sigma-3B-adaptin|sigma-adaptin 3b
Swissprots	Q53H83 B2R677 B4DGQ3 P59780
Accessions	EAX02071 EAX02072 EAX02073 EAX02074 EAX02075 P59780 AK222698 BAD96418 AK294712 BAG57864 AK312467 BAG35374 AL109702 AL110108 AW402906 BC002785 AAH02785 BC007773 AAH07773 BC010020 AAH10020 BC010615 BX098014 DA268327 DA337392 DA464242 DA752479 DA777624 DB322370 DC340463 DC410373 DQ892982 ABM83908 DQ896230 ABM87229 DR158459 X99459 CAA67824 NM_005829 NP_005820 NR_023361 NR_037582
Function	Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Subcellular Location	Golgi apparatus. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. {ECO:0000250}.
Tissue Specificity	Present in all adult tissues examined. {ECO:0000269|PubMed:9118953}.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AP3S2 full length protein - ab160896 from Abcam Category Protein Source Wheat germ Species Human

Human AP3S2 protein fragment - ab160897 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Recombinant Human AP3S2 Protein - H00010239-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human AP3S2 Protein - H00010239-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

AP3S2-Antibody-N-term-Blocking-Peptide - BP16494a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AP3S2 Protein (OPPA01359) - OPPA01359 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human Assembly Protein Complex 3 protein - orb80922 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

AP3 complex subunit sigma-2 - H00010239-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

AP3 complex subunit sigma-2 - H00010239-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

AP3 complex subunit sigma-2 - H00010239-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

AP3 complex subunit sigma-2 - H00010239-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human AP3S2 - 228-10062-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human AP3S2 - 228-10062-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human AP3S2 - 228-10062-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

AP3S2 fusion protein - ag7565 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

AP3S2 fusion protein - ag7950 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human AP3S2 Protein - BP002119-PRO-452 from Syd Labs Category Protein Prices $160.00, $4,800.00 Sizes 10 µg, 1 mg Source E. Coli-derived. Species Human

AP3S2 Human - GWB-A9AE99 from Genway Biotech Category Protein Prices $75.00, $165.00, $7,085.00 Sizes 2 μg, 10 μg, 1000 μg Species Human

Recombinant Human AP3S2, T7-tagged - AP3S2-71H from Creative Biomart Category Protein Source Escherichia coli .

Assembly Protein Complex 3 Human - NKX-983 from Reagent Proteins Category Protein Prices $348.00, $6,752.00 Sizes 10.00 µg, 1 mg Source E.coli Species Human

Recombinant Human AP-3 complex subunit sigma-2(AP3S2) - CSB-YP001880HU CSB-EP001880HU CSB-BP001880HU CSB-MP001880HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

AP3 complex subunit sigma-2 / AP3S2 - TP301104 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

AP-3 complex subunit sigma-2 (AP3S2) , Recombinant Protein - MBS1425972 from MyBioSource Category Protein Prices $1,400.00, $1,400.00, $1,865.00, $1,865.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Orangutan

AP-3 complex subunit sigma-2 (AP3S2) , Recombinant Protein - MBS967495 from MyBioSource Category Protein Prices $1,400.00, $1,400.00, $1,865.00, $1,865.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Assembly Protein Complex 3 Subunit-2, Recombinant Protein - MBS143006 from MyBioSource Category Protein Prices $140.00, $205.00, $6,045.00 Sizes 2 µg, 10 µg, 1 mg Source E Coli

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