SLC38A2

Gene Symbol	SLC38A2
Entrez Gene	54407
Alt Symbol	ATA2, PRO1068, SAT2, SNAT2
Species	Human
Gene Type	protein-coding
Description	solute carrier family 38, member 2
Other Description	amino acid transporter 2|amino acid transporter A2|protein 40-9-1|sodium-coupled neutral amino acid transporter 2|system A amino acid transporter 2|system A transporter 1|system N amino acid transporter 2
Swissprots	Q9NVA8 Q9P2G5 Q6ZMG2 Q6IA88 Q96QD8 Q9HAV3
Accessions	EAW57900 EAW57901 EAW57902 Q96QD8 AB037803 BAA92620 AF116620 AAF71044 AF259799 AAK38510 AF298897 AAG24618 AJ344099 CAC51434 AK001700 BAA91846 AK172784 BAD18765 AK291644 BAF84333 AK293858 BAG57253 BC016909 BC029379 AAH29379 BC040342 AAH40342 CR457267 CAG33548 DA725217 DQ891801 ABM82727 DQ894985 ABM85911 XM_005268983 XP_005269040 XR_944589 NM_001307936 NP_001294865 NM_018976 NP_061849
Function	Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood- brain barrier and in the supply of maternal nutrients to the fetus through the placenta. {ECO:0000269|PubMed:10930503, ECO:0000269|PubMed:15922329}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:15561425, ECO:0000269|PubMed:16616430}; Multi-pass membrane protein {ECO:0000269|PubMed:15561425, ECO:0000269|PubMed:16616430}. Note=Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes (By similarity). Enriched in the somatodendritic compartment of neurons, it is also detected at the axonal shaft but excluded from the nerve terminal. {ECO:0000250}.
Tissue Specificity	Ubiquitously expressed. Widely expressed in the central nervous system with higher concentrations in caudal regions. Expressed by glutamatergic and GABAergic neurons together with astrocytes and other non-neuronal cells in the cerebral cortex (at protein level). {ECO:0000269|PubMed:10930503, ECO:0000269|PubMed:15561425, ECO:0000269|PubMed:16616430}.
Top Pathways	Protein digestion and absorption, GABAergic synapse, Glutamatergic synapse

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SLC38A2 full length protein - ab153368 from Abcam Category Protein Source Wheat germ Species Human

Human SLC38A2 full length protein - ab153369 from Abcam Category Protein Source Wheat germ Species Human

SLC38A2 / SNAT2 Blocking Peptide - LS-E11644 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC38A2 Recombinant Protein - H00054407-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human SLC38A2 Protein - H00054407-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SLC38A2-Antibody-C-term-Blocking-Peptide - BP18342b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SLC38A2 Protein Lysate (APL10207) - APL10207 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

SLC38A2 Protein Lysate (APL10208) - APL10208 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

SLC38A2 Protein Lysate (APL10209) - APL10209 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

SLC38A2 - H00054407-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

SLC38A2 - H00054407-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

SLC38A2 - H00054407-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SLC38A2 - H00054407-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SNAT2 (W190) Peptide - BS9254P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

SLC38A2 Protein - NBP1-88872PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SNAT2 Blocking Peptide - abx162038 from Abbexa Category Peptide Species Human

SLC38A2 Protein Lysate - orb333186 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

SLC38A2 Peptide, Human - M34GP14549H from Creative Peptides Category Peptide Source Synthetic. Species Human

SNAT2 Blocking Peptide - CBP4827 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

Sodium-coupled neutral amino acid transporter 2 (SLC38A2), Recombinant Protein - MBS7096133 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Sodium-coupled neutral amino acid transporter 2 (SLC38A2), Recombinant Protein - MBS1187164 from MyBioSource Category Protein Prices $2,075.00, $2,535.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Chimpanzee

SLC38A2 fusion protein - Ag23082 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

SNAT2 peptide - orb315971 from Biorbyt Category Peptide

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