Gene Symbol | LRRC8E |
---|---|
Entrez Gene | 80131 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat containing 8 family, member E |
Other Description | leucine-rich repeat-containing protein 8E|volume-regulated anion channel subunit LRRC8E |
Swissprots | Q7L236 B3KR78 Q2YDY3 Q6NSJ5 Q9H5H8 Q8N3B0 |
Accessions | EAW68969 Q6NSJ5 AK027073 BAB15648 AK091134 BAG52290 AL834474 CAD39133 AM393515 CAL38392 BC022216 AAH22216 BC070089 AAH70089 BC108252 AAI08253 BX538180 CB049178 CD109368 CF593782 DA447942 XM_011528319 XP_011526621 NM_001268284 NP_001255213 NM_001268285 NP_001255214 NM_025061 NP_079337 |
Function | Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8E constitutes a pore-forming subunit or whether it is closely associated with the pore (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
LRRC8E (L-15) - sc-243366 from Santa Cruz Biotechnology
|
||||||||
LRRC8E (X-24) - sc-133764 from Santa Cruz Biotechnology
|
||||||||
Anti-LRRC8E antibody - ab201188 from Abcam
|
||||||||
Anti-LRRC8E Antibody (aa531-580) - LS-C81483 from LifeSpan Bioscience
|
||||||||
LRRC8E Antibody - NBP1-60062 from Novus Biologicals
|
||||||||
LRRC8E Antibody - NBP1-82078 from Novus Biologicals
|
||||||||
Anti-LRRC8E antibody produced in rabbit - AV49916 from Sigma-Aldrich
|
||||||||
LRRC8E antibody - middle region (ARP49916_P050) - ARP49916_P050 from Aviva Systems Biology
|
||||||||
LRRC8E antibody, Internal - GTX45962 from GeneTex
|
||||||||
LRRC8E antibody - 70R-6993 from Fitzgerald
|
||||||||
LRRC8E Antibody - abx036597 from Abbexa
|
||||||||
LRRC8E Antibody - 30-556 from ProSci
|
||||||||
LRRC8E Antibody - E306638 from Enogene
|
||||||||
LRRC8E Antibody - GWB-MR702I from Genway Biotech
|
||||||||
LRRC8E, Polyclonal Antibody - MBS5302114 from MyBioSource
|
||||||||
LRRC8E Antibody,HRP conjugated - CSB-PA743982LB01HU from Cusabio
|
||||||||
LRRC8E Antibody,FITC conjugated - CSB-PA743982LC01HU from Cusabio
|
||||||||
LRRC8E Antibody,Biotin conjugated - CSB-PA743982LD01HU from Cusabio
|
||||||||
LRRC8E Antibody - CSB-PA743982LA01HU from Cusabio
|
||||||||
LRRC8E antibody - TA338693 from Acris Antibodies
|
||||||||
Anti-LRRC8E antibody produced in rabbit - HPA020466 from Sigma-Aldrich
|
||||||||
LRRC8E antibody (Biotin) - orb355484 from Biorbyt
|
||||||||
LRRC8E antibody - orb355483 from Biorbyt
|
||||||||
Anti-LRRC8E Antibody A11883 - A11883 from Boster Bio
|
||||||||
LRRC8E, Polyclonal Antibody - MBS1499916 from MyBioSource
|