LRRC8E

Gene Symbol LRRC8E
Entrez Gene 80131
Alt Symbol -
Species Human
Gene Type protein-coding
Description leucine rich repeat containing 8 family, member E
Other Description leucine-rich repeat-containing protein 8E|volume-regulated anion channel subunit LRRC8E
Swissprots Q7L236 B3KR78 Q2YDY3 Q6NSJ5 Q9H5H8 Q8N3B0
Accessions EAW68969 Q6NSJ5 AK027073 BAB15648 AK091134 BAG52290 AL834474 CAD39133 AM393515 CAL38392 BC022216 AAH22216 BC070089 AAH70089 BC108252 AAI08253 BX538180 CB049178 CD109368 CF593782 DA447942 XM_011528319 XP_011526621 NM_001268284 NP_001255213 NM_001268285 NP_001255214 NM_025061 NP_079337
Function Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8E constitutes a pore-forming subunit or whether it is closely associated with the pore (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

LRRC8E CRISPR/Cas9 KO Plasmid (h) - sc-413343 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8E HDR Plasmid (h) - sc-413343-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8E Double Nickase Plasmid (h) - sc-413343-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8E Double Nickase Plasmid (h2) - sc-413343-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8E CRISPR Activation Plasmid (h) - sc-413343-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8E CRISPR Activation Plasmid (h2) - sc-413343-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8E Lentiviral Activation Particles (h) - sc-413343-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8E Lentiviral Activation Particles (h2) - sc-413343-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8E siRNA (h) - sc-97525 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LRRC8E shRNA Plasmid (h) - sc-97525-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LRRC8E shRNA (h) Lentiviral Particles - sc-97525-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU034641 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12768 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12768 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08215 from Sigma-Aldrich

Category miRNA

LRRC8E siRNA (Human) - CRJ2763 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LRRC8E (NM_025061.4) - SHH334891 from Creative biogene

Category siRNA
Species Reactivities Human

Human LRRC8E siRNA - orb273264 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LRRC8E shRNA Plasmid (Human) - CHJ2763 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LRRC8E miRNA 3'UTR clone - MiUTR3H-12671 from Creative biogene

Species Reactivities Human
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