RNPS1

Gene Symbol RNPS1
Entrez Gene 10921
Alt Symbol E5.1
Species Human
Gene Type protein-coding
Description RNA binding protein S1, serine-rich domain
Other Description RNA-binding protein S1, serine-rich domain|RNA-binding protein with serine-rich domain 1|SR protein|SR-related protein LDC2
Swissprots B4DZU7 A8K1P0 Q15287 Q32P25 O75308 B7ZA17 B4DDU8 Q9NYG3 Q8WY42
Accessions EAW85516 EAW85517 EAW85518 EAW85519 EAW85520 EAW85521 EAW85522 Q15287 AB445101 BAI99736 AF015608 AAC39791 AF247662 AAF72519 AF274003 AAL56665 AK021799 AK091886 AK092131 AK289955 BAF82644 AK293343 BAG56859 AK303100 BAG64209 AK316132 BAH14503 AL520572 AL559988 BC001659 AAH01659 BC001838 AAH01838 BC108316 AAI08317 BG716139 BI819738 BQ059026 DA062271 DA728900 DA732377 DA818573 DQ574166 DQ895514 ABM86440 EU176344 ABW03795 HY012482 L37368 AAA92859 XM_005255048 XP_005255105 XM_005255049 XP_005255106 NM_001286625 NP_001273554 NM_001286626 NP_001273555 NM_001286627 NP_001273556 NM_006711 NP_006702 NM_080594 NP_542161 NR_104485
Function Part of pre- and post-splicing multiprotein mRNP complexes. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. The ASAP complex can inhibit RNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Enhances the formation of the ATP-dependent A complex of the spliceosome. Involved in both constitutive splicing and, in association with SRP54 and TRA2B/SFRS10, in d
Subcellular Location Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein. Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and UAP56 in the nucleus and nuclear speckles.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:8543184}.
Top Pathways RNA transport, mRNA surveillance pathway

RNPS1 (D-14) - sc-19940 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-RNPS1 antibody - ab79233 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RNPS1 antibody (ab79233) at 1 µg/mlLane 1 : : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 3 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 4 : A431 (Human epithelial carcinoma cell line) Whole Cell LysateLane 5 : U2OS (Human osteosarcoma cell line) Whole Cell Lysate Lane 6 : JEG-3 (Human placental choriocarcinoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-RNPS1 antibody - ab56806 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56806 RNPS1 antibody at 1ug/ml.

Anti-SR Protein / RNPS1 Antibody (clone 7G8) - LS-C139424 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7G8

Anti-SR Protein / RNPS1 Antibody (N-Terminus) - LS-C346026 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of RNPS1 Antibody with human HepG2 Whole Cell lysate.

RNPS1 Antibody - NBP1-92343 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RNPS1 Antibody [NBP1-92343] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10Lane 2: Negative control (vector only transfected HEK293T lysate)Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells)

RNPS1 Antibody (2G11) - H00010921-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G11

RNPS1 Antibody (7G8) - H00010921-M05 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7G8

RNPS1 Antibody - H00010921-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-RNPS1 antibody produced in rabbit - HPA044014 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RNPS1: <B>Cat. No. HPA044014</B>: Immunohistochemical staining of human hippocampus shows strong nuclear positivity in neuronal cells.

Monoclonal Anti-RNPS1 antibody produced in mouse - SAB1404879 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7G8
<B>Immunoblotting</B><BR/>Monoclonal Anti-RNPS1: <B>Cat. No. SAB1404879</B>: Antibody concentration: 1 μg/mL. Specific band of ~35.1 kDa using immunogen protein lysate.

Monoclonal Anti-RNPS1 antibody produced in mouse - WH0010921M4 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G11
<B>Immunoblotting</B><BR/>Monoclonal Anti-RNPS1, <B>Cat. No. WH0010921M4</B> used at the antibody concentration: 1 μg/mL. Specific band of ~35.13 kDa using immunogen protein lysate.

RNPS1 Antibody - N-terminal region (ARP73889_P050) - ARP73889_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RNPS1 antibody - 70R-19936 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

RNPS1 antibody - 10555-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
293 cell were subjected to SDS PAGE followed by western blot with 10555-1-AP(RNPS1 Antibody) at dilution of 1:1000

RNPS1 antibody - H00010921-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

RNPS1 antibody - H00010921-M04 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G11

RNPS1 antibody - H00010921-M05 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7G8

RNPS1 antibody - 10555-1-AP from Proteintech Group

Prices $279.00
Sizes con: 20 μg/150μl
Host Rabbit
Clonality Polyclonal
HEK-293 cells were subjected to SDS PAGE followed by western blot with 10555-1-AP(RNPS1 antibody) at dilution of 1:1000

RNPS1, Monoclonal Antibody - MBS6007019 from MyBioSource

Prices $580.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G11

Anti-RNPS1 (aa 158-239) polyclonal antibody - DPAB-DC319 from Creative Diagnostics

Host Mouse
Clonality Polyclonal

RNPS1 Polyclonal Antibody - PA5-35967 from Thermo Fisher Scientific

Prices $309.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of RNPS1 using Various whole cell extracts (30 ?g). Samples were loaded onto a 10% SDS-PAGE gel and probed with a RNPS1 polyclonal antibody (Product # PA5-35967) at a dilution of 1:1000.

RNA binding protein S1, serine-rich domain , Polyclonal Antibody - MBS710572 from MyBioSource

Prices $230.00, $500.00
Sizes 50 µl, 150 µl
Host Rabbit
Clonality Polyclonal

Anti-RNA binding protein S1, serine-rich domain - 08A010921 from MP Biomedicals

Prices $456.30
Sizes 100 μg
Host Mouse
Clonality Monoclonal
Clone 2G11

RNPS1 antibody - GTX129789 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-RNPS1 antibody used in Western blot. GTX129789
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