RNPS1

Gene Symbol	RNPS1
Entrez Gene	10921
Alt Symbol	E5.1
Species	Human
Gene Type	protein-coding
Description	RNA binding protein S1, serine-rich domain
Other Description	RNA-binding protein S1, serine-rich domain|RNA-binding protein with serine-rich domain 1|SR protein|SR-related protein LDC2
Swissprots	B4DZU7 A8K1P0 Q15287 Q32P25 O75308 B7ZA17 B4DDU8 Q9NYG3 Q8WY42
Accessions	EAW85516 EAW85517 EAW85518 EAW85519 EAW85520 EAW85521 EAW85522 Q15287 AB445101 BAI99736 AF015608 AAC39791 AF247662 AAF72519 AF274003 AAL56665 AK021799 AK091886 AK092131 AK289955 BAF82644 AK293343 BAG56859 AK303100 BAG64209 AK316132 BAH14503 AL520572 AL559988 BC001659 AAH01659 BC001838 AAH01838 BC108316 AAI08317 BG716139 BI819738 BQ059026 DA062271 DA728900 DA732377 DA818573 DQ574166 DQ895514 ABM86440 EU176344 ABW03795 HY012482 L37368 AAA92859 XM_005255048 XP_005255105 XM_005255049 XP_005255106 NM_001286625 NP_001273554 NM_001286626 NP_001273555 NM_001286627 NP_001273556 NM_006711 NP_006702 NM_080594 NP_542161 NR_104485
Function	Part of pre- and post-splicing multiprotein mRNP complexes. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. The ASAP complex can inhibit RNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Enhances the formation of the ATP-dependent A complex of the spliceosome. Involved in both constitutive splicing and, in association with SRP54 and TRA2B/SFRS10, in d
Subcellular Location	Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein. Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and UAP56 in the nucleus and nuclear speckles.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:8543184}.
Top Pathways	RNA transport, mRNA surveillance pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RNPS1 full length protein - ab132616 from Abcam Category Protein Source Wheat germ Species Human

Human RNPS1 full length protein - ab169913 from Abcam Category Protein Source E. coli Species Human

Human RNPS1 peptide - ab88206 from Abcam Category Peptide

Human RNPS1 protein fragment - ab161200 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human RNPS1 Protein - H00010921-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human RNPS1 Protein - H00010921-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RNPS1 - H00010921-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RNPS1 - H00010921-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RNPS1 - H00010921-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RNPS1 - H00010921-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RNPS1 fusion protein - Ag0844 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human RNPS1, GST-tagged - RNPS1-2354H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human RNA-binding protein with serine-rich domain 1(RNPS1) - CSB-YP621869HU CSB-EP621869HU CSB-BP621869HU CSB-MP621869HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RNPS1 (transcript variant 2) - TP315882 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RNPS1 (transcript variant 1) - TP317673 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RNPS1 Recombinant Protein Antigen - NBP1-92343PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RNPS1-Blocking-Peptide-N-Term - BP21998a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RNPS1 Peptide, Human - M34GP13456H from Creative Peptides Category Peptide Source Synthetic. Species Human

RNA-binding protein with serine-rich domain 1 (RNPS1), Recombinant Protein - MBS1400340 from MyBioSource Category Protein Prices $1,065.00, $1,065.00, $1,290.00, $1,290.00, $1,660.00, $1,660.00, $2,125.00, $2,125.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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